EBT3 Radiochromic film response in time-dependent thermal environment and water submersion conditions: Its clinical relevance and uncertainty estimation

IF 2.8 3区 物理与天体物理 Q3 CHEMISTRY, PHYSICAL Radiation Physics and Chemistry Pub Date : 2024-11-17 DOI:10.1016/j.radphyschem.2024.112403
Gaurav Trivedi , Pushpendra P. Singh , Arun S. Oinam
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Abstract

Aim

This study aimed to find the thermal and humidity-dependent behavior of EBT3 film. The changes in the film sensitivity as well as the dosimetric region of interest in the small-size film due to its storage and setup condition were evaluated.

Material and methods

Three sets of films were kept at three different thermal storage conditions. 15 films from each set were kept at 2 °C, 20 °C, and 40 °C storage conditions for 24 h and 48 h pre- and post-irradiation. The humidity effect (water submersion) on the film in terms of the film's edge diffusion, and change in the optical density at the central region of the film was estimated by keeping the films underwater.

Results

The mean relative film sensitivity was found 1.107 ± 0.123 and 0.966 ± 0.028 respectively for the films stored at 40 °C and 2 °C with respect to the sensitivity of the films that were kept at room temperature (20 °C) each for 48 h. The dosimetric result shows that the measured dose in the dose range (2–20 Gy) was overestimated by 7.01 % (percentage mean dose difference (MDD)) in the films stored at 40 °C for 48 h. In contrast, it was underestimated by −4.54 % (MDD) in the films stored at 2 °C for 48 h compared to those kept at an ambient room temperature of 20 °C (MDD = 0.24%). The water-diffusion rate at the border of the EBT3 film used in this study was 0.23 mm/h. An increment of 6.8% in the optical density at the central region of the film was observed for the unexposed control film kept underwater for 24 h. The combined standard uncertainty due to five different sources of uncertainties was 2.91%.

Conclusion

The sensitivity of the EBT3 film kept at 40 °C is always higher (overestimate) whereas lower (underestimate) for the films kept at 2 °C as compared to the films at normal room temperature. The correction for the changes in the net optical density due to its storage condition (thermal effect) and the dosimetry condition of water submersion (humidity effect) must be incorporated into the current protocols of film-dosimetry if the facility cannot have temperature-controlled film storage environment and if the film immersion under water is more than 4 h.
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EBT3 射频变色膜在随时间变化的热环境和水浸条件下的反应:其临床意义和不确定性估计
本研究旨在发现 EBT3 薄膜随热量和湿度变化的特性。研究评估了小尺寸薄膜的灵敏度以及剂量测定区域因其储存和设置条件而发生的变化。
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来源期刊
Radiation Physics and Chemistry
Radiation Physics and Chemistry 化学-核科学技术
CiteScore
5.60
自引率
17.20%
发文量
574
审稿时长
12 weeks
期刊介绍: Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.
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