J F Navarro-Gracia, F J Gómez-Romero, F J Lozano-García, R Ortí-Lucas, J A Delgado-De Los Reyes, M Fernández-Prada, R Herruzo-Cabrera
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引用次数: 0
Abstract
Background: The Zero Surgical Infection Project (ZSIP) in Spain is a nation-wide program to prevent surgical site infections (SSI), sponsored by the Ministry of Health. The program includes the application of 5 key preventive measures (PM) grouped in a bundle: Perioperative antibiotic prophylaxis (PAP), skin antisepsis (SA), hair removal (HR), normothermia (NT) and normoglycemia (NG).
Aim: To assess the effectiveness of the bundle of 5 ZSIP preventive measures, applied in a set of Spanish public hospitals over the period 2017-2021, under standard conditions of surgical healthcare in Spain.
Methods: This was a prospective cohort study of 33,240 patients from the ZSIP Registry (National Database Network). It includes surveillance of SSI data of selected surgical interventions, compliance data and other risk factors. Compliance with the PM was verified through a specific checklist. The intervention and comparison groups were, those patients compliant and those non-compliant with the 5PM bundle, respectively. We calculated adjusted odds ratio (OR) and preventive fraction (PF) using logistic regression.
Findings: Overall SSI rate for patients in the compliant vs. not compliant 5PM bundle groups were 4.77% vs. 6.90%. Overall compliance of 5 PM bundle was 35.9%, and was higher in PAP (87.2%), SA (82.2%) and HR (78.7%). Compliance of 5PM bundle of ZSIP presents a PF of 32%, adjusted OR 0.68 (IC 95% 0.60-0.76).
Conclusion: The preventive intervention of the ZSIP implemented over the period 2017-21 in Spain achieved a significant level of effectiveness against SSI.
期刊介绍：
The Journal of Hospital Infection is the editorially independent scientific publication of the Healthcare Infection Society. The aim of the Journal is to publish high quality research and information relating to infection prevention and control that is relevant to an international audience.
The Journal welcomes submissions that relate to all aspects of infection prevention and control in healthcare settings. This includes submissions that:
provide new insight into the epidemiology, surveillance, or prevention and control of healthcare-associated infections and antimicrobial resistance in healthcare settings;
provide new insight into cleaning, disinfection and decontamination;
provide new insight into the design of healthcare premises;
describe novel aspects of outbreaks of infection;
throw light on techniques for effective antimicrobial stewardship;
describe novel techniques (laboratory-based or point of care) for the detection of infection or antimicrobial resistance in the healthcare setting, particularly if these can be used to facilitate infection prevention and control;
improve understanding of the motivations of safe healthcare behaviour, or describe techniques for achieving behavioural and cultural change;
improve understanding of the use of IT systems in infection surveillance and prevention and control.
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