Shubhashisha Mohanty , Birasen Behera , Abhinav Sinha , Madhusmita Bal , Sanghamitra Pati , Prakash Kumar Sahoo
{"title":"Mass drug administration to eliminate lymphatic filariasis: A population-based coverage and compliance study in Eastern India","authors":"Shubhashisha Mohanty , Birasen Behera , Abhinav Sinha , Madhusmita Bal , Sanghamitra Pati , Prakash Kumar Sahoo","doi":"10.1016/j.cegh.2024.101860","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Neglected tropical diseases (NTDs) like lymphatic filariasis (LF) affect over 1 billion people globally, with India being a significant hotspot. Challenges persist despite global and national efforts, including the World Health Organization's (WHO) Global Program to Eliminate Lymphatic Filariasis (GPELF) and India's National Filaria Control Programme. We conducted a study to assess the coverage and compliance of mass drug administartion (MDA) to improve LF elimination efforts in the Khordha district of Odisha, India.</div></div><div><h3>Methods</h3><div>A sample of 2281 participants, including both males and females aged two years or older, was chosen through multistage stratified sampling. These participants were interviewed using a semi-structured questionnaire. Collected data regarding socio-demographic characteristics, knowledge of filariasis, coverage and consumption of MDA drugs were analyzed. Descriptive statistics were applied to determine coverage and compliance, with results presented alongside a 95 % confidence interval.</div></div><div><h3>Results</h3><div>In our study, coverage and compliance rates were 86.36 % and 91.12 % for Albendazole, while 84.12 % and 90.62 % for DEC respectively. Fear of side effects was the reason for most of the participants' non-consumption. The coverage rate was low in urban areas because of gated communities and a lack of confidence in drug distributors.</div></div><div><h3>Conclusion</h3><div>This recent round of MDA was effective but still fear of side effects and lack of awareness were major challenges for the compliance of MDA drugs that need to be addressed for the complete eradication of LF.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"30 ","pages":"Article 101860"},"PeriodicalIF":2.3000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Epidemiology and Global Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213398424003579","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Neglected tropical diseases (NTDs) like lymphatic filariasis (LF) affect over 1 billion people globally, with India being a significant hotspot. Challenges persist despite global and national efforts, including the World Health Organization's (WHO) Global Program to Eliminate Lymphatic Filariasis (GPELF) and India's National Filaria Control Programme. We conducted a study to assess the coverage and compliance of mass drug administartion (MDA) to improve LF elimination efforts in the Khordha district of Odisha, India.
Methods
A sample of 2281 participants, including both males and females aged two years or older, was chosen through multistage stratified sampling. These participants were interviewed using a semi-structured questionnaire. Collected data regarding socio-demographic characteristics, knowledge of filariasis, coverage and consumption of MDA drugs were analyzed. Descriptive statistics were applied to determine coverage and compliance, with results presented alongside a 95 % confidence interval.
Results
In our study, coverage and compliance rates were 86.36 % and 91.12 % for Albendazole, while 84.12 % and 90.62 % for DEC respectively. Fear of side effects was the reason for most of the participants' non-consumption. The coverage rate was low in urban areas because of gated communities and a lack of confidence in drug distributors.
Conclusion
This recent round of MDA was effective but still fear of side effects and lack of awareness were major challenges for the compliance of MDA drugs that need to be addressed for the complete eradication of LF.
期刊介绍:
Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.