Clinical Epidemiology and Global Health最新文献

Attack rate and determinants of malaria outbreak in Ethiopia: A systematic review and meta-analysis 埃塞俄比亚疟疾暴发的发病率和决定因素：系统回顾和荟萃分析

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health

Pub Date : 2025-04-24 DOI: 10.1016/j.cegh.2025.102045

Diriba Etana Tola , Azeb Haile Tesfaye , Lencho Kajela Solbana , Shalama Lekasa Nagari , Zenebu Begna Bayissa , Eshetu Ejeta Chaka

Background

Malaria remains a public health challenge in Ethiopia. Despite progress in reducing cases and deaths, there has been a resurgence. This highlights the need to identify driving factors for malaria outbreaks and sustain progress toward elimination. This study aims to determine the overall attack rate of malaria outbreaks and identify the key determinants.

Methods

The study was registered with PROSPERO with the registration code CRD42025645940. Databases, including PubMed, EMBASE, Google Scholar, Google, and Web of Science. Analyzed using R version 4.2.3 and Stata version 17.0.

Results

In this study, the pooled estimated attack rate of malaria outbreaks in Ethiopia was 3 % (95 % CI: 2 %–5 %). Presence of stagnant water (OR = 3.45; 95 % CI: 2.06, 4.84), staying outside at night (OR = 3.79; 95 % CI: 2.39, 5.20), not using insecticide-treated bed nets (OR = 3.52; 95 % CI: 3.13, 3.92), lack of knowledge about transmission and preventions methods (OR = 4.73; 95 % CI: 1.67, 7.80), knowing transmission and prevention methods (OR = 0.38; 0.13, 0.64), presence of breeding sites (OR = 3.40; 95 % CI: 1.35, 5.44), not using indoor chemical sprays (OR = 3.19; 1.76, 4.63).

Conclusion

To combat these outbreaks, a comprehensive approach is recommended, involving environmental management to eliminate mosquito breeding sites, public health education, and increasing access to preventive tools such as ITNs and indoor residual spraying. Addressing these determinants effectively can reduce malaria outbreaks, leading to a decrease in morbidity and mortality, and improve public health outcomes.

在埃塞俄比亚，疟疾仍然是一项公共卫生挑战。尽管在减少病例和死亡方面取得了进展，但死灰复燃。这突出表明需要确定疟疾暴发的驱动因素，并在消除疟疾方面保持进展。这项研究的目的是确定疟疾暴发的总发病率，并确定关键的决定因素。方法本研究在PROSPERO注册，注册码CRD42025645940。数据库，包括PubMed， EMBASE，谷歌Scholar，谷歌和Web of Science。使用R 4.2.3版本和Stata 17.0版本进行分析。结果埃塞俄比亚疟疾暴发的综合估计发病率为3% （95% CI: 2% - 5%）。存在死水(OR = 3.45；95% CI: 2.06, 4.84)，夜间呆在室外(OR = 3.79；95% CI: 2.39, 5.20)，未使用驱虫蚊帐(OR = 3.52；95% CI: 3.13, 3.92)，缺乏关于传播和预防方法的知识(OR = 4.73；95% CI: 1.67, 7.80)，了解传播和预防方法(OR = 0.38；0.13, 0.64)，存在繁殖场所(OR = 3.40；95% CI: 1.35, 5.44)，不使用室内化学喷雾剂(OR = 3.19；1.76, 4.63)。结论为防治这些疫情，建议采取综合措施，包括环境管理、消除蚊虫滋生场所、公共卫生教育、增加获得ITNs和室内滞留喷洒等预防工具。有效处理这些决定因素可以减少疟疾暴发，从而降低发病率和死亡率，并改善公共卫生成果。

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引用次数: 0

Circulating Asprosin and Neuregulin-4 in metabolic dysfunction-associated steatotic liver disease (MASLD): A systematic review and meta-analysis 循环Asprosin和Neuregulin-4在代谢功能障碍相关脂肪变性肝病（MASLD）中的作用：一项系统综述和荟萃分析

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health

Pub Date : 2025-04-23 DOI: 10.1016/j.cegh.2025.102041

Roshan Kumar Mahat , Vedika Rathore

Background

Adipokines, such as asprosin and neuregulin 4 (Nrg4), are implicated in the pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD) and may function as potential diagnostic biomarkers and therapeutic targets. The objective of this meta-analysis is to compare the circulating levels of asprosin and Nrg4 between populations with MASLD and those without the condition.

Methods

A systematic review and meta-analysis were conducted in accordance with the PRISMA guidelines. Databases including PubMed, Scopus, and Europe PMC were systematically searched for observational studies published until October 7, 2024. Inclusion criteria consisted of studies that reported extractable data on circulating asprosin and Nrg4 in populations with and without MASLD. Random-effects models were employed to calculate standardized mean differences (SMDs) and mean differences (MDs) with 95 % confidence intervals (CIs). Heterogeneity among studies was assessed using Cochrane's Q test, as well as I² and Tau² statistics. Furthermore, sensitivity analysis and publication bias were evaluated to ensure the robustness of the findings.

Results

Ten studies were included, with four analysing asprosin and six analysing Nrg4. Patients with MASLD exhibited significantly higher circulating asprosin levels (SMD = 0.82, 95 % CI: 0.49–1.15; p < 0.01; I² = 65 %) and lower Nrg4 levels (SMD = −1.12, 95 % CI: 1.77 to −0.46; p < 0.01; I² = 94 %) compared to non-MASLD individuals. Sensitivity analyses confirmed the robustness of these findings.

Conclusions

Elevated asprosin and reduced Nrg4 levels are associated with MASLD, highlighting their potential as biomarkers and therapeutic targets. Further studies are warranted to validate these findings.

ad -因子，如asprosin和神经调节蛋白4 (Nrg4)，与代谢功能障碍相关的脂肪变性肝病（MASLD）的发病机制有关，可能作为潜在的诊断生物标志物和治疗靶点。本荟萃分析的目的是比较MASLD患者和非MASLD患者之间asprosin和Nrg4的循环水平。方法按照PRISMA指南进行系统评价和meta分析。系统检索了PubMed、Scopus和Europe PMC等数据库，检索了截至2024年10月7日发表的观察性研究。纳入标准包括报告有MASLD和无MASLD人群中循环asprosin和Nrg4可提取数据的研究。采用随机效应模型计算标准化平均差（SMDs）和平均差（MDs），置信区间为95%。采用Cochrane’s Q检验以及I2和Tau2统计量评估研究间的异质性。此外，对敏感性分析和发表偏倚进行评估，以确保研究结果的稳健性。结果共纳入10篇研究，其中4篇分析asprosin， 6篇分析Nrg4。MASLD患者表现出明显较高的循环asprosin水平(SMD = 0.82, 95% CI: 0.49-1.15；p & lt;0.01;I2 = 65%)和较低的Nrg4水平(SMD = - 1.12, 95% CI: 1.77 ~ - 0.46；p & lt;0.01;I2 = 94%)与非masld个体相比。敏感性分析证实了这些发现的稳健性。结论asprosin升高和Nrg4水平降低与MASLD相关，突出了它们作为生物标志物和治疗靶点的潜力。需要进一步的研究来证实这些发现。

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引用次数: 0

The relationship between age, obesity indices, and cardiometabolic risk factors in Women: Findings from a point-of-care health screening in South Sulawesi, Indonesia 年龄、肥胖指数和妇女心脏代谢危险因素之间的关系：来自印度尼西亚南苏拉威西的一项即时保健筛查的发现

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health

Pub Date : 2025-04-23 DOI: 10.1016/j.cegh.2025.102048

Ika Yustisia , Liong Boy Kurniawan , Tenri Esa , Syahrijuita , Sri Astuti Thamrin

Background

Metabolic syndrome (MetS) significantly increases the risk of diabetes mellitus and cardiovascular disease. The prevalence of MetS is higher in women due to factors such as pregnancy, menopause, and lifestyle habits. In Indonesia, MetS affects 21.66 % of the population, with women being disproportionately affected. Biomarkers may improve diagnosis; early detection is essential for care and prevention. This study evaluates health screening results among women in South Sulawesi, Indonesia, to provide insights into MetS prevalence and risk factors.

Methods

Using point-of-care devices, this study analyzed data sources on health examination results from a community service activity attended by 139 female participants undergoing a comprehensive health assessment, including anthropometric, blood pressure, and biochemical measurements.

Results

The study's findings revealed a range of significant health concerns among the female participants, including hypertension, hyperuricemia, hypercholesterolemia, and obesity. These conditions were found to increase with age. The study also identified specific cutoff values for body weight and body mass index that could predict hypertension, 57.7 kg and 24.8 kg/m2, respectively, and the visceral fat index that could indicate potential hyperuricemia was 8.8.

Conclusion

Metabolic health screening identifies obesity, hypertension, hypercholesterolemia, and hyperuricemia as key concerns for women's health in South Sulawesi, Indonesia. These findings highlight the need for further validation and targeted interventions to improve women's metabolic health.

背景代谢综合征（MetS）显著增加了患糖尿病和心血管疾病的风险。由于怀孕、更年期和生活习惯等因素，女性的代谢综合征患病率较高。在印度尼西亚，代谢综合征影响了21.66%的人口，其中女性受到的影响尤为严重。生物标志物可以改善诊断；早期发现对于护理和预防至关重要。本研究评估了印度尼西亚南苏拉威西省妇女的健康筛查结果，以深入了解代谢综合征的患病率和风险因素。方法本研究使用护理点设备，分析了139名女性参与者参加的社区服务活动的健康检查结果数据来源，这些参与者接受了全面的健康评估，包括人体测量、血压和生化测量。结果研究结果显示，女性参与者存在一系列严重的健康问题，包括高血压、高尿酸血症、高胆固醇血症和肥胖。这些情况随着年龄的增长而增加。该研究还确定了可以预测高血压的体重和体重指数的具体临界值，分别为57.7公斤和24.8公斤/平方米，可以指示潜在高尿酸血症的内脏脂肪指数为8.8。结论代谢健康筛查将肥胖、高血压、高胆固醇血症和高尿酸血症确定为印度尼西亚南苏拉威西妇女健康的关键问题。这些发现强调了进一步验证和有针对性的干预措施的必要性，以改善女性的代谢健康。

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引用次数: 0

Trends in overweight and obesity among reproductive-age women in sub-Saharan African countries from 1990 to 2030: Progress towards 2030 SDG nutrition targets 1990年至2030年撒哈拉以南非洲国家育龄妇女超重和肥胖趋势：实现2030年可持续发展目标营养具体目标的进展

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health

Pub Date : 2025-04-23 DOI: 10.1016/j.cegh.2025.102044

A.A. Tareke , A. Mohammed , Y. Ali , A. Muche

Objective

We aimed to determine the trends of overweight and obesity among women of reproductive age (WRA) in sub-Saharan countries from 1990 to 2030. We also calculated the likelihood of achieving the Sustainable Development Goals (SDGs) in this region.

Study design

Repeated cross-sectional study.

Methods

The study employed 122 nationally representative cross-sectional survey datasets from 32 countries within sub-Saharan Africa. A Bayesian linear regression model was employed to determine overweight and obesity estimates, complete with 95 % credible intervals, based on data from 769,724 women.

Results

Twenty-eight countries (87.5 %) showed an increasing trend compared with the 1990 overweight value. Only four countries (Burundi, Congo, Lesotho, and Sierra Leone) showed a decreasing trend. In all countries except Lesotho, the proportion of overweight has increased since 2015. From 2024 to 2030, no country is expected to experience a decline in overweight prevalence. Of the 32 countries, 31 (96.88 %) have an increasing obesity rate. Only Sierra Leone shows a decreasing trend from 1990 to 2024. The prevalence of obesity has increased in all 32 countries since the start of the SDGs. No country is on track to meet the SDG target of eliminating all forms of malnutrition related overweight and obesity by 2030.

Conclusions

The increasing prevalence of overweight and obesity among WRA in SSA is a significant concern. Aggressive interventions are required to address this problem. New initiatives beyond the SDG era may also be needed to prevent the ongoing surge.

目的：研究1990年至2030年撒哈拉以南非洲国家育龄妇女超重和肥胖的趋势。我们还计算了该地区实现可持续发展目标（sdg）的可能性。研究设计重复横断面研究。该研究采用了来自撒哈拉以南非洲32个国家的122个具有全国代表性的横断面调查数据集。基于769,724名妇女的数据，采用贝叶斯线性回归模型来确定超重和肥胖的估计，并完成95%的可信区间。结果28个国家（87.5%）与1990年的超重值相比有上升趋势。只有四个国家（布隆迪、刚果、莱索托和塞拉利昂）呈现下降趋势。除莱索托外，所有国家的超重比例自2015年以来都有所增加。从2024年到2030年，预计没有一个国家的超重流行率会下降。在32个国家中，有31个国家（96.88%）的肥胖率呈上升趋势。从1990年到2024年，只有塞拉利昂呈现下降趋势。自可持续发展目标启动以来，所有32个国家的肥胖患病率都有所上升。没有哪个国家有望实现到2030年消除一切形式的与营养不良有关的超重和肥胖的可持续发展目标。结论SSA地区WRA中超重和肥胖患病率的上升值得关注。需要采取积极的干预措施来解决这一问题。可能还需要在可持续发展目标时代之外采取新的举措，以防止持续的激增。

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引用次数: 0

Prevalence of young-onset diabetes and associated physical activity profile in southern India 印度南部青少年糖尿病患病率及相关身体活动概况

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health

Pub Date : 2025-04-23 DOI: 10.1016/j.cegh.2025.102040

Anupama Harihar , G. Arun Maiya , Sahana Shetty , Shivashankar K.N. , Shyamasunder Bhat N.

Background/objective

A temporal shift is noticed in the age of diagnosis of type 2 diabetes mellitus among young adults globally. Physical inactivity is a significant contributor to the higher prevalence of young-onset diabetes in India. This study aims to estimate the prevalence of young-onset diabetes in southern India and to identify the physical activity level and barriers in young adults.

Methods

This is a cross-sectional study including individuals aged 18–40 years. A total of 273 participants were included by random selection of individuals attending a tertiary hospital for routine checkups. In the first stage, the prevalence of type 2 diabetes was estimated using capillary blood glucose level evaluation. The second stage includes the profiling of physical activity & identification of barriers to physical activity among physically inactive individuals using a self-reported questionnaire.

Result

The overall prevalence of young-onset type 2 diabetes was found to be 17.2 %. Pre-existing type 2 diabetes was 11.3 %, while 5.8 % of new cases were found with no previous history of diabetes. In males, the prevalence was 10.6 %, whereas in females, it was 6.5 %. The majority of individuals with young-onset type 2 diabetes were physically inactive, and the most common barriers identified were lack of time, willpower, and energy.

Conclusion

This study reveals a high prevalence of type 2 diabetes below the age of 40 years in India. Screening for diabetes by the age of 25 years is highly recommended. Management strategies are needed to overcome the identified barriers and promote physical activity in young adults.

背景/目的在全球范围内，年轻成年人确诊 2 型糖尿病的年龄发生了时间上的变化。在印度，缺乏运动是导致年轻糖尿病发病率较高的一个重要原因。本研究旨在估算印度南部年轻糖尿病患者的发病率，并确定年轻人的体育锻炼水平和障碍。通过随机抽取在一家三甲医院接受常规检查的人员，共纳入了 273 名参与者。第一阶段，通过毛细血管血糖水平评估来估计 2 型糖尿病的患病率。第二阶段包括体力活动和运动量分析；通过自我报告问卷调查，确定不爱运动者的体力活动障碍。既往有2型糖尿病病史者占11.3%，而5.8%的新病例既往没有糖尿病病史。男性的发病率为 10.6%，女性为 6.5%。大多数年轻的 2 型糖尿病患者缺乏运动，最常见的障碍是缺乏时间、意志力和精力。强烈建议在 25 岁之前进行糖尿病筛查。需要制定管理策略，克服已发现的障碍，促进年轻人的体育锻炼。

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引用次数: 0

Epidemiological profile and treatment of cystic echinococcosis hospitalized cases in Morocco between 2011 and 2021 2011年至2021年摩洛哥囊性包虫病住院病例的流行病学概况和治疗

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health

Pub Date : 2025-04-22 DOI: 10.1016/j.cegh.2025.102035

Ilham Benmoujjane , Souad Bouhout , Aicha mehdioui , Houda Chebli , Meryem Zabarra , Mohammed Akrim , Hassan Chrifi , Touria Benamar

Background/objective

Cystic Echinococcosis (CE) is a globally spread zoonotic disease. In Morocco, CE is endemic. The objective was to study Morocco's epidemiological profile and management of hospitalized patients with CE.

Methods

This research was done retrospectively over 11 years (2011–2021). It included 7385 cases from all regions of Morocco.

Results

Between 2011 and 2021, the annual incidence decreased from 4.55 to 1.18 (per 100,000 population). The patients' ages varied from one to 115 years. The sex ratio of women to men was 1.54. Rural areas accounted for 62.96 % of the patients. The diagnostic method commonly used was the ultrasound (67.62 %). The liver (80.85 %) was the most affected organ, followed by the lungs (15.68 %). Type I cysts accounted for 56.35 % of all HC cases. Surgery was performed in 97.33 % of the patients, with 57.01 % being conservative. The outcome was favorable for 98.48 % of the cases. The Average Length of Stay (ALOS) in the hospital for CE patients was 11 days.

Conclusion

Significant progress has been made towards achieving the goal of CE eradication by 2030, but Morocco still faces a significant threat due to the high number of hospitalized cases and resulting deaths.

背景/目的囊性棘球蚴病是一种全球传播的人畜共患疾病。在摩洛哥，CE是一种地方病。目的是研究摩洛哥的流行病学概况和对住院CE患者的管理。方法回顾性研究11年（2011-2021年）。其中包括来自摩洛哥所有地区的7385例病例。结果2011 - 2021年，年发病率从4.55例（每10万人）下降到1.18例（每10万人）。患者的年龄从1岁到115岁不等。男女性别比为1.54。农村占62.96%。常用的诊断方法为超声（67.62%）。肝脏（80.85%）是最主要的脏器，其次是肺（15.68%）。I型囊肿占所有HC病例的56.35%。97.33%的患者行手术治疗，其中57.01%为保守治疗。98.48%的病例预后良好。CE患者平均住院时间（ALOS）为11天。结论：摩洛哥在实现到2030年根除小儿麻痹症的目标方面取得了重大进展，但由于住院病例和由此导致的死亡人数众多，摩洛哥仍然面临重大威胁。

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引用次数: 0

Unmet needs to achieve disease control among patients with hypertension and diabetes, Pathanamthitta, Kerala, India, 2023: A mixed methods study. 高血压和糖尿病患者未满足的疾病控制需求，Pathanamthitta，喀拉拉邦，印度，2023：一项混合方法研究。

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health

Pub Date : 2025-04-19 DOI: 10.1016/j.cegh.2025.102036

Abey Sushan, Malu Mohan, Aby Robinson, Anjali Krishna, Boopathi Kangusamy, Sendhilkumar Muthappan, Abdulkader Suliankatchi Rizwan

Background

This study addresses unmet needs in managing hypertension and diabetes at public health institutions in Pathanamthitta district, Kerala, India, highlighting the significance of non-pharmacological approaches and psychosocial support.

Methods

This mixed-methods cross-sectional study was conducted in two phases: a quantitative phase followed by a qualitative phase. 18 Primary Health Centers (PHCs), one urban PHC, and six Community Health Centers (CHCs) were selected through simple random sampling. Patients were interviewed using a structured, interviewer-administered questionnaire. Quantitative data were analyzed and presented as frequencies and percentages, while qualitative data were transcribed and thematically analyzed to identify key themes.

Results

We interviewed 346 patients, of whom 144 (41.6 %) had only hypertension, 57 (16.5 %) had only diabetes, and 145 (41.9 %) had both conditions. Hypertension was under control in 89 (31.4 %) patients, while diabetes was under control in 51 (27.7 %) patients. Among the 89 patients with controlled hypertension, most had unmet needs for information about their condition (91.0 %), diet (90.9 %), and exercise (88.8 %). Unmet need for information about disease condition was reported by 44 (88·0 %) of 50 patients who achieved control of diabetes compared to 127 (94·8 %) among 134 patients who did not achieve control. Qualitative data identified meal preparation and household chores as major barriers to effective disease management.

Conclusion

Unmet needs are high across domains like information about disease, drug, and exercise. Establishment of community-based support groups for patients with hypertension and/or diabetes to enable collective motivation for sustained lifestyle changes can be explored to achieve better control.

背景：本研究解决了印度喀拉拉邦Pathanamthitta地区公共卫生机构在管理高血压和糖尿病方面未满足的需求，强调了非药物方法和社会心理支持的重要性。方法采用混合方法进行横断面研究，分为定量和定性两个阶段。采用简单随机抽样的方法，选取18所初级卫生中心、1所城市初级卫生中心和6所社区卫生中心。采用结构化的、由访谈者管理的问卷对患者进行访谈。定量数据被分析并以频率和百分比的形式呈现，而定性数据被转录并按主题进行分析，以确定关键主题。结果346例患者中，144例（41.6%）合并高血压，57例（16.5%）合并糖尿病，145例（41.9%）合并高血压和糖尿病。89例（31.4%）患者高血压得到控制，51例（27.7%）患者糖尿病得到控制。在89例高血压控制患者中，大多数患者对其病情（91.0%）、饮食（90.9%）和运动（88.8%）的信息需求未得到满足。50例糖尿病控制成功的患者中有44例（88.0%）未满足疾病状况信息需求，而134例未控制成功的患者中有127例（94.8%）未满足疾病状况信息需求。定性数据表明，膳食准备和家务劳动是有效疾病管理的主要障碍。结论未满足需求在疾病信息、药物信息、运动信息等领域均较高。为高血压和/或糖尿病患者建立以社区为基础的支持小组，使集体动力持续改变生活方式，以达到更好的控制。

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引用次数: 0

Prevalence of swallow fatigue and its relationship with self reported swallowing difficulties among community dwelling older adults in the Indian population 在印度社区居住的老年人中，吞咽疲劳的患病率及其与自我报告吞咽困难的关系

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health

Pub Date : 2025-04-18 DOI: 10.1016/j.cegh.2025.102034

Uzair Chilwan , K. Vijaya Kumar , Sudhin Karuppali , Venkataraja U. Aithal , Thejaswi Dodderi , Sahlah Shameer , Radish Kumar Balasubramanium

Problem considered

Swallowing fatigue significantly impacts older adults, affecting daily activities and increasing the risk of disability. This study explored the prevalence of swallowing fatigue among healthy young, middle-aged, and older adults and its relationship with self-reported swallowing difficulties.

Method

A cross-sectional study was conducted with 389 participants. The Swallowing and Eating-Related Fatigue Scale in Kannada (SERF-K) and self-reported scales (EAT-10K, DHI-K) were used. Reliability was assessed through internal consistency and test-retest reproducibility.

Results

SERF-K demonstrated good internal consistency (Cronbach's α = 0.752), with individual item consistency ranging from 0.729 to 0.849. Older adults had a mean SERF-K score of 12.1, with 41.5 % reporting swallowing fatigue. A moderate correlation (r = 0.56) was observed between swallowing fatigue and self-reported difficulties.

Conclusion

These findings emphasize the necessity of recognizing swallow fatigue as a crucial factor in understanding swallowing difficulties across different age groups. While older adults exhibited a higher prevalence of swallowing fatigue, the presence of this symptom in young and middle aged adults also highlights the importance of early identification and early intervention. Addressing swallowing fatigue can contribute to improving overall quality of life and reducing the risk of disability related to swallowing in the general population.

考虑的问题吞咽疲劳对老年人的影响很大，会影响日常活动并增加残疾风险。本研究探讨了吞咽疲劳在健康的年轻人、中年人和老年人中的普遍程度及其与自我报告的吞咽困难之间的关系。采用卡纳达语吞咽和进食相关疲劳量表（SERF-K）和自我报告量表（EAT-10K、DHI-K）。结果SERF-K显示出良好的内部一致性（Cronbach's α = 0.752），单个项目的一致性在0.729到0.849之间。老年人的 SERF-K 平均得分为 12.1 分，其中 41.5% 的人报告有吞咽疲劳。吞咽疲劳与自我报告的吞咽困难之间存在中等程度的相关性（r = 0.56）。虽然老年人的吞咽疲劳发生率较高，但青年和中年人出现这种症状也凸显了早期识别和早期干预的重要性。解决吞咽疲劳问题有助于提高整体生活质量，降低普通人群因吞咽而致残的风险。

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引用次数: 0

Acceptance of booster dose of COVID-19 vaccine and factors influencing it among health care workers at Tikur Anbessa specialized hospital, in Addis Ababa, Ethiopia 埃塞俄比亚亚的斯亚贝巴蒂库尔·安贝萨专科医院医护人员对COVID-19疫苗加强剂的接受情况及其影响因素

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health

Pub Date : 2025-04-17 DOI: 10.1016/j.cegh.2025.102027

Bahja Ahmed Mohammed, Zelalem Tilahun Tesfaye, Fikreselam Habte Hailemariam, Chalelgn Kassaw Belete

Background

The COVID-19 booster dose (BD) was introduced to enhance protection after the initial vaccination series. However, its acceptance remains low, particularly among healthcare workers (HCWs). This study aimed to assess BD acceptance among HCWs at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, and identify the factors influencing their decision.

Methodology

A cross-sectional study was conducted among 423 HCWs from May to June 2022. Data were collected using a self-administered questionnaire and a convenient sampling technique. Descriptive and inferential analyses were performed using SPSS version 25. Binary logistic regression was applied to identify factors associated with BD acceptance.

Results

A total of 399 HCWs completed the survey, with 51.4 % male, 80.5 % health professionals, and 60.2 % aged 18–30 years. More than half had no prior COVID-19 infection. Despite 86.5 % holding favorable attitudes toward BD, only 28.6 % accepted it. BD acceptance was significantly higher among HCWs aged 31–40 years (AOR = 2.21), 41–50 years (AOR = 4.14), and over 50 years (AOR = 6.00) compared to those aged 18–30 years. Married individuals (AOR = 1.82), those with post-vaccination COVID-19 infection (AOR = 1.94), and those with a favorable attitude toward BD (AOR = 16.74) were more likely to accept it.

Conclusion

Less than one-third of HCWs accepted the COVID-19 BD. Older age, marital status, prior post-vaccination COVID-19 infection, and positive attitudes toward vaccination were significant predictors. Low acceptance among HCWs may influence public confidence in immunization, necessitating targeted interventions to improve uptake.

背景COVID-19加强剂（BD）的引入是为了在初次接种系列疫苗后加强保护。然而，其接受度仍然很低，尤其是在医护人员（HCWs）中。本研究旨在评估埃塞俄比亚亚的斯亚贝巴Tikur Anbessa专科医院医护人员对BD的接受程度，并确定影响他们做出决定的因素。方法 2022年5月至6月，对423名医护人员进行了横断面研究。采用自填式问卷和方便抽样技术收集数据。使用 SPSS 25 版本进行了描述性和推论性分析。结果共有 399 名医护人员完成了调查，其中 51.4% 为男性，80.5% 为卫生专业人员，60.2% 年龄在 18-30 岁之间。超过一半的人之前未感染过 COVID-19。尽管有 86.5% 的人对 BD 持赞成态度，但只有 28.6% 的人接受它。与 18-30 岁的人相比，31-40 岁（AOR = 2.21）、41-50 岁（AOR = 4.14）和 50 岁以上（AOR = 6.00）的医务工作者对 BD 的接受程度明显更高。已婚者（AOR = 1.82）、接种 COVID-19 后感染者（AOR = 1.94）和对 BD 持赞成态度者（AOR = 16.74）更有可能接受 BD。年龄较大、婚姻状况、接种后曾感染 COVID-19 和对接种的积极态度是重要的预测因素。医护人员的低接受度可能会影响公众对免疫接种的信心，因此有必要采取有针对性的干预措施来提高接种率。

{"title":"Acceptance of booster dose of COVID-19 vaccine and factors influencing it among health care workers at Tikur Anbessa specialized hospital, in Addis Ababa, Ethiopia","authors":"Bahja Ahmed Mohammed, Zelalem Tilahun Tesfaye, Fikreselam Habte Hailemariam, Chalelgn Kassaw Belete","doi":"10.1016/j.cegh.2025.102027","DOIUrl":"10.1016/j.cegh.2025.102027","url":null,"abstract":"<div><h3>Background</h3><div>The COVID-19 booster dose (BD) was introduced to enhance protection after the initial vaccination series. However, its acceptance remains low, particularly among healthcare workers (HCWs). This study aimed to assess BD acceptance among HCWs at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, and identify the factors influencing their decision.</div></div><div><h3>Methodology</h3><div>A cross-sectional study was conducted among 423 HCWs from May to June 2022. Data were collected using a self-administered questionnaire and a convenient sampling technique. Descriptive and inferential analyses were performed using SPSS version 25. Binary logistic regression was applied to identify factors associated with BD acceptance.</div></div><div><h3>Results</h3><div>A total of 399 HCWs completed the survey, with 51.4 % male, 80.5 % health professionals, and 60.2 % aged 18–30 years. More than half had no prior COVID-19 infection. Despite 86.5 % holding favorable attitudes toward BD, only 28.6 % accepted it. BD acceptance was significantly higher among HCWs aged 31–40 years (AOR = 2.21), 41–50 years (AOR = 4.14), and over 50 years (AOR = 6.00) compared to those aged 18–30 years. Married individuals (AOR = 1.82), those with post-vaccination COVID-19 infection (AOR = 1.94), and those with a favorable attitude toward BD (AOR = 16.74) were more likely to accept it.</div></div><div><h3>Conclusion</h3><div>Less than one-third of HCWs accepted the COVID-19 BD. Older age, marital status, prior post-vaccination COVID-19 infection, and positive attitudes toward vaccination were significant predictors. Low acceptance among HCWs may influence public confidence in immunization, necessitating targeted interventions to improve uptake.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"33 ","pages":"Article 102027"},"PeriodicalIF":2.3,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mapping the research landscape of lifestyle modification in PCOS management: A 10 year bibliometric analysis 生活方式改变在多囊卵巢综合征治疗中的研究前景：10年文献计量分析

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health

Pub Date : 2025-04-12 DOI: 10.1016/j.cegh.2025.102024

Rohit Gautam , Asmitha Bhateja , Neena Malhotra , Taruna Arora

Objective

Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder affecting women of reproductive age, with significant implications for metabolic, reproductive, and psychological health. The objective of the study is to conduct a 10-year bibliometric analysis of research trends on lifestyle modifications in PCOS treatment.

Methodology

This bibliometric analysis examines the 10-year research landscape (2015–2024) on lifestyle modification for PCOS management, analyzing global trends, key contributors, and thematic advancements using Web of Science data and VOS viewer tool. A total 2214 studies has been selected for bibliometric analysis.

Result

Results indicate a steady increase in research output, highest between 2022 and 2023, underscoring the growing recognition of lifestyle interventions. Monash University emerged as the leading institution, driving high-impact research, and fostering global collaborations. The USA, China, and England dominates the research landscape, while emerging nations like India and Iran contribute culturally tailored interventions. Key authors, including Helena Teede and Lisa Moran, play central roles, reflected in their high publication counts and citation impacts. Keyword analysis highlights weight loss, obesity, insulin resistance, and quality of life as primary research focuses, with recent trends (2021–2024) exploring gut micro biota optimization, oxidative stress, and mindfulness-based interventions.

Conclusion

Despite progress, contributions from Africa and South America highlight the need for global equity in research. This analysis highlights dynamic research shifts, emerging trends, and the critical need for global equity and collaboration to advance evidence-based lifestyle interventions for PCOS management.

目的多囊卵巢综合征（PCOS）是一种影响育龄妇女的常见内分泌疾病，对代谢、生殖和心理健康具有重要影响。本研究的目的是对PCOS治疗中生活方式改变的研究趋势进行10年文献计量学分析。本文献计量分析研究了10年（2015-2024）关于生活方式改变对PCOS管理的研究概况，分析了全球趋势、主要贡献者和专题进展，使用Web of Science数据和VOS查看工具。共选取2214项研究进行文献计量学分析。结果表明，研究产出稳步增长，在2022年至2023年期间达到最高水平，突显出人们对生活方式干预的认识日益增强。莫纳什大学成为领先的机构，推动高影响力的研究，促进全球合作。美国、中国和英国在研究领域占据主导地位，而印度和伊朗等新兴国家则贡献了适合其文化的干预措施。包括Helena Teede和Lisa Moran在内的主要作者发挥了核心作用，这反映在他们的高发表量和引用影响上。关键词分析强调减肥、肥胖、胰岛素抵抗和生活质量是主要的研究重点，最近的趋势（2021-2024）是探索肠道微生物群优化、氧化应激和基于正念的干预。尽管取得了进展，但来自非洲和南美洲的贡献强调了全球研究公平的必要性。这一分析强调了动态的研究转变、新趋势以及全球公平和合作的迫切需要，以推进以证据为基础的生活方式干预对多囊卵巢综合征的管理。

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引用次数: 0