Recent advances on Pd schiff base catalysts in suzuki-miyaura cross-coupling reaction: A review

Abstract

Carbon-carbon cross-coupling organic transformations are crucial in organic chemistry, but achieving them without a catalyst is challenging. Various catalysts based on complex have been developed to facilitate these reactions. Firstly, ligands based on phosphine were used, but their sensitive nature and toxic led researchers to turn to ligands based on Schiff base. These ligands are stable, simple to synthesize, and produce a variety of transition metal complexes. Ligands based on Schiff base are typically synthesized from the condensation reaction between carbonyl compounds and an amino group, and their complexes along with transition metal are widely used in different carbon–carbon cross-coupling organic transformations. In particular, palladium complexes, are well-known catalytic systems in carbon-carbon cross-coupling organic transformations such as the Suzuki-Miyaura cross-coupling organic transformations. This review focuses on the application of Pd Schiff base ligands in Suzuki-Miyaura reaction.