Feasibility of new thresholds for coronary artery calcium score using low-tube voltage protocols in postmortem computed tomography1

IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Forensic Imaging Pub Date : 2024-11-09 DOI:10.1016/j.fri.2024.200615
Kyoung Eun Cheon , Se-min Oh , Sung Wook Choi , Man-Seok Han , Jang Gyu Cha , Heon Lee , Minju Lee , Sookyoung Lee
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Abstract

Objective

To validate whether low tube voltage scans of 100 kilovolt-peak (kVp) and 80 kVp for measuring coronary artery calcium score (CACS) using computed tomography (CT) yield comparable results to the standard protocol of 120 kVp using postmortem CT (PMCT).

Materials and Methods

We obtained scans for cadavers where CAC was observed on PMCT scans. In addition to the standard protocol, tube voltage scans were also obtained under conditions of 100 kVp and 80 kVp. We obtained a newly adapted threshold under low tube voltage and compared them with the standard protocol.

Results

The CACS was 851±1421 (p=0.99) and 861±1433 (p=0.99) for the 120-kVp and 100-kVp scans, respectively, and 845±1390 (p=0.99) for the 80-kVp scan using the newly adapted threshold. The 120-kVp and 100-kVp scans demonstrated an almost perfect correlation (r=0.99996, p<0.0001). In the Bland–Altman analysis, the 9 5% limits of agreement ranged from -44 to 25. Similarly, the CACS obtained using the adapted threshold for the 80-kVp scan also demonstrated an excellent correlation with the standard 120-kVp scan (r=0.99993, p<0.0001). In the Bland–Altman analysis, the 95 % limits of agreement ranged from -62 to 75. The effective radiation dose was 2.21±0.064 mSv (p<0.0001) for the 120-kVp scan, 1.35±0.070 mSv (p<0.0001) for the 100-kVp scan, and 0.72±0.48 mSv (p<0.0001) for the 80-kVp scan.

Conclusion

This study suggests that PMCT can be used to measure CACS at low tube voltages and that significant dose reductions in patients can be expected in clinical practice.
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死后计算机断层扫描中使用低管电压协议进行冠状动脉钙化评分的新阈值的可行性1
目的验证使用计算机断层扫描(CT)测量冠状动脉钙化评分(CACS)时,100 千伏-峰值(kVp)和 80 千伏-峰值(kVp)的低管电压扫描结果是否与使用尸检 CT(PMCT)测量 120 千伏-峰值(kVp)的标准方案结果相当。除标准方案外,我们还在 100 kVp 和 80 kVp 的条件下进行了管电压扫描。结果120 kVp和100 kVp扫描的CACS分别为851±1421(P=0.99)和861±1433(P=0.99),使用新调整的阈值进行80 kVp扫描的CACS为845±1390(P=0.99)。120-kVp 和 100-kVp 扫描显示出几乎完美的相关性(r=0.99996,p<0.0001)。在 Bland-Altman 分析中,9.5% 的一致性范围在-44 到 25 之间。同样,使用 80 kVp 扫描的适应阈值获得的 CACS 与标准 120 kVp 扫描也显示出极好的相关性(r=0.99993,p<0.0001)。在 Bland-Altman 分析中,95 % 的一致性范围为 -62 至 75。120 kVp 扫描的有效辐射剂量为 2.21±0.064 mSv(p<0.0001),100 kVp 扫描的有效辐射剂量为 1.35±0.070 mSv(p<0.0001),80 kVp 扫描的有效辐射剂量为 0.72±0.48 mSv(p<0.0001)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Forensic Imaging
Forensic Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.20
自引率
27.30%
发文量
39
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