Perla R Colunga-Pedraza, Fernando De la Garza-Salazar, Héctor A Vaquera-Alfaro, Andrés Gómez-De León, Mónica Bustillos-Muñoz, Luz Tarín-Arzaga, Olga Cantú-Rodríguez, César Homero Gutiérrez-Aguirre, David Gómez-Almaguer
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引用次数: 0
Abstract
Therapies such as corticosteroids, thrombopoietin receptor agonists and immunomodulators have been consistently under the spotlight in the search for a better treatment for immune thrombocytopenia (ITP). However, none of them has been widely embraced as a new standard. In this pilot study, we investigated feasibility, safety and preliminary efficacy of romiplostim, low-dose rituximab and high-dose dexamethasone for newly diagnosed ITP. We conducted a single-centre single-arm pilot. One-month treatment adherence was 100%. The 1-month overall response rate was 92.3%. Complete response occurred in 11 (84.6%) patients. Median duration of response was 4.13 monts (range 0.2-25). No serious adverse events presented.
期刊介绍：
The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.
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