Development of a Calculator to Determine Individualized Opioid Doses for Treatment of Vaso-Occlusive Episodes for Sickle Cell Disease in the Emergency Department
Patricia L. Kavanagh MD (is Associate Professor, Department of Pediatrics, Chobanian & Avedisian School of Medicine, Boston University, and Research Faculty, Center of Excellence in Sickle Cell Disease, Boston Medical Center.), John J Strouse MD, PhD (is Associate Professor, Departments of Medicine and Pediatrics, Duke University School of Medicine, and Hematologist, Duke University Comprehensive Sickle Cell Center.), Judith A. Paice PhD, RN (is Research Professor, Northwestern University Feinberg School of Medicine.), Stephanie O. Ibemere PhD, RN (is Assistant Professor, Duke University School of Nursing.), Paula Tanabe PhD, RN (is Professor, Duke University School of Nursing and Duke University School of Medicine. Please address correspondence to Patricia L. Kavanagh)
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Abstract
Sickle cell disease (SCD) is a life-limiting multisystem disease primarily affecting individuals of African and Latinx descent. Its most common complication is painful vaso-occlusive episodes (VOEs), which is also the most common reason individuals with SCD seek care in the emergency department (ED). National guidelines recommend the use of standardized approaches to pain management in the ED, preferably using pain management plans tailored to each patient. However, no standard approach to developing these plans exists. This article describes the development of an opioid calculator to help SCD clinicians create individualized plans to better manage acute painful VOE in the ED setting.