Attitudes and Experiences of Patients Regarding Gender-Specific Aspects of Pain Management.

IF 2 Q3 PHARMACOLOGY & PHARMACY Pharmacy Pub Date : 2024-11-22 DOI:10.3390/pharmacy12060175
Carolin Alexandra Boldt, Dirk Keiner, Norman Best, Thilo Bertsche
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Abstract

Background: Biological, pharmacological, and socio-cultural aspects influence gender-specific effects in pain management.

Methods: Gender-specific aspects of pain management were assessed in a rural outpatient center via semi-structured patient interview: (i) general gender aspects (total population) from 1 = "fully disagree" to 5 = "fully agree"; and (ii) individual pain (matched pairs) via numeric analog scale (NAS) from 0 = "no pain" to 10 = "maximum pain". Patient charts were assessed for pain management (WHO-ladder).

Results: In total, 113 patients were enrolled (59.18 [SD: 12.76] years, 46% female, 54% male, 0% diverse), and 42 were matched into female-male pairs. (i) Women and men agreed that men and women should be treated equally despite biological differences (median: 5 [women] vs. 5 [men]; p = 0.789). As a reason for gender-specific aspects, "medication concentration" was reported more frequently by women (p = 0.038) and "no answer" by men (p = 0.014). (ii) Mean value (SD) of pain (NAS) was 4.0 (SD 2.3) for women and 3.3 (SD 2.6) for men (p = 0.215) with a positive correlation between pain management escalation (WHO-ladder) and the pain score (NAS) only in men (r = 0.704, p = 0.001). Women rather reported an influence of adverse drug reactions on treatment contentment than men (p = 0.042).

Conclusions: Although patients pleaded for gender-independent equal treatment, gender-specific differences in pain therapy were found.

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患者对疼痛治疗中性别差异的态度和体验。
背景:生物学、药理学和社会文化方面对疼痛治疗的性别特异性影响:方法:在农村门诊中心,通过对患者进行半结构化访谈,评估了疼痛治疗中的性别特异性:在一个农村门诊中心,通过半结构化患者访谈对疼痛治疗中的性别特异性进行了评估:(i) 一般性别方面(总人口),从 1 ="完全不同意 "到 5 ="完全同意";(ii) 通过数字模拟量表(NAS)评估个体疼痛(配对),从 0 ="无疼痛 "到 10 ="最大疼痛"。对患者病历进行疼痛管理评估(WHO-阶梯):共有 113 名患者(59.18 [SD: 12.76]岁,46% 为女性,54% 为男性,0% 为不同性别)参加了此次研究,其中 42 名患者为男女配对。(i) 女性和男性都认为,尽管存在生理差异,但男性和女性应受到同等对待(中位数:5 [女性] 对 5 [男性];P = 0.789)。作为性别差异的原因,女性报告 "药物浓度 "的频率更高(p = 0.038),而男性报告 "无答案 "的频率更高(p = 0.014)。(ii) 女性疼痛(NAS)的平均值(标清)为 4.0(标清 2.3),男性为 3.3(标清 2.6)(p = 0.215),只有男性的疼痛管理升级(WHO-阶梯)与疼痛评分(NAS)呈正相关(r = 0.704,p = 0.001)。与男性相比,女性更愿意报告药物不良反应对治疗满意度的影响(p = 0.042):结论:尽管患者恳求与性别无关的平等治疗,但在疼痛治疗中还是发现了性别差异。
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来源期刊
Pharmacy
Pharmacy PHARMACOLOGY & PHARMACY-
自引率
9.10%
发文量
141
审稿时长
11 weeks
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