Beam quality correction factors for dose measurements around 192Ir brachytherapy sources.

IF 2 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of Applied Clinical Medical Physics Pub Date : 2024-11-27 DOI:10.1002/acm2.14575
Zoi Thrapsanioti, Vasiliki Peppa, Costas J Hourdakis, Pantelis Karaiskos, Aristea Lekatou, Evaggelos Pantelis
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Abstract

Purpose: To provide beam quality correction factors ( k Q , Q o ${k}_{Q,Qo}$ ) for detectors used in 192Ir brachytherapy dosimetry measurements.

Materials and methods: Ten detectors were studied, including the PTW 30013 and Exrading12 Farmer large cavity chambers, seven medium (0.1-0.3 cm3) and small (< 0.1 cm3) cavity chambers, and a synthetic microdiamond detector. The kQ,Qo correction factors were calculated at distances from 1 to 10 cm away from an 192Ir source, using the EGSnrc Monte Carlo (MC) code. All detectors were calibrated in a 60Co 10 × 10 cm2 reference field provided by standard calibration laboratories. The impact of the central electrode, stem and wall on the detectors' responses in 192Ir photon energies was investigated. An experimental procedure was additionally applied for dose measurements around a microSelectron-v2 192Ir high dose rate (HDR) brachytherapy source using a motorized water phantom.

Results: Farmer chambers underestimated the dose near the source due to signal volume averaging effects, resulting in kQ,Qo values ranging from 1.177 and 1.317 at 1 cm, decreasing with distance to between 0.980 and 1.005 at 10 cm. Small cavity volume detectors should be used close to the source. The kQ,Qo for the studied small and medium cavity volume detectors were found to be close to unity (within 1.3%), showing also a small dependence on source-to-detector distance, except for ion chambers containing high-Z materials in their construction. The presence of high-Z materials caused an overresponse in these detectors, resulting in kQ,Qo values ranging from 0.950 at 1 cm to 0.729 at 10 cm away from the source. A dose rate constant of (1.114 ± 0.023)cGyh-1U-1 was found in agreement with the literature (within 0.5%).

Conclusions: kQ,Qo values were calculated for dose measurements around 192Ir brachytherapy sources. Farmer chambers should be preferred for measurements at increased distances, whereas small or medium cavity volume detectors, not containing high-Z materials, should be used close to the source.

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用于 192Ir 近距离放射源周围剂量测量的光束质量校正系数。
目的:为 192Ir 近距离放射剂量测定测量中使用的探测器提供射束质量校正系数(k Q , Q o ${k}_{Q,Qo}$ ):研究了十个探测器,包括 PTW 30013 和 Exrading12 Farmer 大型腔室、七个中型(0.1-0.3 cm3)和小型(3)腔室以及一个合成微钻石探测器。使用 EGSnrc 蒙特卡罗(MC)代码计算了距离 192Ir 源 1 到 10 厘米的 kQ,Qo 校正因子。所有探测器都在标准校准实验室提供的 60Co 10 × 10 cm2 基准场中进行了校准。研究了中心电极、杆和壁对探测器在 192Ir 光子能量下响应的影响。此外,还利用电动水模型对微电子-v2 192Ir 高剂量率(HDR)近距离放射源周围的剂量进行了测量:结果:由于信号体积平均效应,法玛室低估了放射源附近的剂量,导致 1 厘米处的 kQ、Qo 值介于 1.177 和 1.317 之间,随着距离的增加,10 厘米处的 kQ、Qo 值降至 0.980 和 1.005 之间。应在靠近光源的地方使用小空腔容积探测器。所研究的小型和中型空腔容积探测器的 kQ,Qo 都接近于统一(在 1.3% 以内),而且与源到探测器的距离关系不大,但在结构上含有高 Z 材料的离子室除外。高 Z 材料的存在导致这些探测器出现过度响应,导致 kQ,Qo 值从距离源 1 厘米处的 0.950 到 10 厘米处的 0.729 不等。剂量率常数为 (1.114 ± 0.023)cGyh-1U-1 ,与文献一致(0.5% 以内)。结论:计算了 192Ir 近距离放射源周围剂量测量的 kQ、Qo 值。在距离较远的地方进行测量时,应首选 Farmer 室,而在靠近放射源的地方则应使用不含高 Z 材料的小型或中型腔容积探测器。
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来源期刊
CiteScore
3.60
自引率
19.00%
发文量
331
审稿时长
3 months
期刊介绍: Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission. JACMP will publish: -Original Contributions: Peer-reviewed, investigations that represent new and significant contributions to the field. Recommended word count: up to 7500. -Review Articles: Reviews of major areas or sub-areas in the field of clinical medical physics. These articles may be of any length and are peer reviewed. -Technical Notes: These should be no longer than 3000 words, including key references. -Letters to the Editor: Comments on papers published in JACMP or on any other matters of interest to clinical medical physics. These should not be more than 1250 (including the literature) and their publication is only based on the decision of the editor, who occasionally asks experts on the merit of the contents. -Book Reviews: The editorial office solicits Book Reviews. -Announcements of Forthcoming Meetings: The Editor may provide notice of forthcoming meetings, course offerings, and other events relevant to clinical medical physics. -Parallel Opposed Editorial: We welcome topics relevant to clinical practice and medical physics profession. The contents can be controversial debate or opposed aspects of an issue. One author argues for the position and the other against. Each side of the debate contains an opening statement up to 800 words, followed by a rebuttal up to 500 words. Readers interested in participating in this series should contact the moderator with a proposed title and a short description of the topic
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