Bone marrow aspirate concentrate for the treatment of fifth metatarsal head stress fracture: a case report.

IF 2.4 4区 医学 Q4 CELL & TISSUE ENGINEERING Regenerative medicine Pub Date : 2024-11-26 DOI:10.1080/17460751.2024.2422193
Hirotaka Nakagawa, Kristen Mitchell, Walter I Sussman
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Abstract

Metatarsal head stress fractures pose treatment challenges with no established consensus. In this article, we introduce a percutaneous treatment involving autologous bone marrow aspirate concentrate (BMAC) injection without surgical fixation in a 21-year-old basketball player with a stress fracture of the right fifth metatarsal head. He underwent this procedure following unsuccessful 8 months of conservative treatment. Twelve weeks after the procedure, a CT scan confirmed complete healing, facilitating his return to sports. This innovative method offers a promising alternative, avoiding the associated morbidity of surgical intervention. Further research, comparing refracture rates with surgical options, is warranted to inform treatment decisions for this uncommon injury and validate the efficacy of percutaneous BMAC injection.

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骨髓抽吸浓缩物治疗第五跖骨头应力性骨折:病例报告。
跖骨头应力性骨折给治疗带来了挑战,目前尚未达成共识。在本文中,我们介绍了一种无需手术固定的经皮治疗方法,该方法涉及自体骨髓抽吸物浓缩物(BMAC)注射,适用于一名右侧第五跖骨头应力性骨折的 21 岁篮球运动员。他在接受了 8 个月的保守治疗未果后接受了该手术。术后 12 周,CT 扫描证实骨折完全愈合,他得以重返赛场。这种创新方法提供了一种很有前景的替代方案,避免了手术治疗带来的发病率。有必要开展进一步的研究,将骨折率与手术方案进行比较,为这种罕见损伤的治疗决策提供依据,并验证经皮 BMAC 注射的疗效。
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来源期刊
Regenerative medicine
Regenerative medicine 医学-工程:生物医学
CiteScore
4.20
自引率
3.70%
发文量
82
审稿时长
6-12 weeks
期刊介绍: Regenerative medicine replaces or regenerates human cells, tissue or organs, to restore or establish normal function*. Since 2006, Regenerative Medicine has been at the forefront of publishing the very best papers and reviews covering the entire regenerative medicine sector. The journal focusses on the entire spectrum of approaches to regenerative medicine, including small molecule drugs, biologics, biomaterials and tissue engineering, and cell and gene therapies – it’s all about regeneration and not a specific platform technology. The journal’s scope encompasses all aspects of the sector ranging from discovery research, through to clinical development, through to commercialization. Regenerative Medicine uniquely supports this important area of biomedical science and healthcare by providing a peer-reviewed journal totally committed to publishing the very best regenerative medicine research, clinical translation and commercialization. Regenerative Medicine provides a specialist forum to address the important challenges and advances in regenerative medicine, delivering this essential information in concise, clear and attractive article formats – vital to a rapidly growing, multidisciplinary and increasingly time-constrained community. Despite substantial developments in our knowledge and understanding of regeneration, the field is still in its infancy. However, progress is accelerating. The next few decades will see the discovery and development of transformative therapies for patients, and in some cases, even cures. Regenerative Medicine will continue to provide a critical overview of these advances as they progress, undergo clinical trials, and eventually become mainstream medicine.
期刊最新文献
Bone marrow aspirate concentrate for the treatment of fifth metatarsal head stress fracture: a case report. Proliferation and differentiation of Wharton's jelly-derived mesenchymal stem cells on prgf-treated hydrogel scaffold. ATMP clinical trials in the UK. Industry updates from the field of stem cell research and regenerative medicine in September 2024. Correction.
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