Beyond Awareness: Hope for a CMV Vaccine! An Introduction to the Conference, "CMV Vaccine Development-How Close Are We?" (27-28 September 2023).

IF 5.2 3区 医学 Q1 IMMUNOLOGY Vaccines Pub Date : 2024-10-29 DOI:10.3390/vaccines12111226
Megan H Pesch, Mark R Schleiss, Stanley A Plotkin, Sallie R Permar, Rajeev Gautam
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Abstract

Congenital cytomegalovirus (cCMV) is the most common infectious cause of disability in children. The major theme of this National Institute of Allergy and Infectious Diseases (NIAID) workshop, "CMV Vaccine Development-How Close Are We?", was to report progress on the development of a pre-conception vaccine that could confer protective immunity for women of child-bearing age. Such a vaccine could result in a reduced cCMV disease burden, although other populations, including solid organ transplant and hematopoietic stem cell transplant patients, could benefit as well. To frame the compelling need for a cCMV vaccine, a keynote lecture by Dr. Megan Pesch, immediate past-president of the National CMV Foundation and a leading cCMV researcher from the University of Michigan, was given. This manuscript provides a summary of Dr. Pesch's presentation from this workshop, which was written as the introductory conference report for the meeting.

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超越认知:CMV 疫苗的希望!会议简介:"CMV 疫苗开发--我们离成功还有多远?
先天性巨细胞病毒(cCMV)是导致儿童残疾的最常见传染病因。美国国家过敏与传染病研究所 (NIAID) 此次研讨会的主题是 "巨细胞病毒疫苗的开发--我们还有多远?",旨在报告可为育龄妇女提供保护性免疫力的孕前疫苗的开发进展。这种疫苗可以减轻 cCMV 疾病负担,但其他人群,包括实体器官移植和造血干细胞移植患者也会从中受益。为了说明对 cCMV 疫苗的迫切需求,美国国家 CMV 基金会前任主席、密歇根大学的主要 cCMV 研究人员 Megan Pesch 博士发表了主题演讲。本手稿提供了 Pesch 博士在此次研讨会上的演讲摘要,并将其作为会议的介绍性会议报告。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Vaccines
Vaccines Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
8.90
自引率
16.70%
发文量
1853
审稿时长
18.06 days
期刊介绍: Vaccines (ISSN 2076-393X) is an international, peer-reviewed open access journal focused on laboratory and clinical vaccine research, utilization and immunization. Vaccines publishes high quality reviews, regular research papers, communications and case reports.
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