Atrophic facial acne scars; bilateral comparison of two microneedle devices.

IF 1.2 4区 医学 Q3 DERMATOLOGY Journal of Cosmetic and Laser Therapy Pub Date : 2024-11-16 Epub Date: 2024-11-26 DOI:10.1080/14764172.2024.2433219
Moetaz El-Domyati, Maha M E Fathi, Rasha T A Abdel-Aziz
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Abstract

Microneedling is a minimally invasive procedure using fine needles to puncture the skin.The aim of this study is to compare the clinical efficacy as well as the histological effects of dermaroller versus dermapen in the management of post-acne atrophic scars.The study was conducted on 10 patients with post-acne atrophic scars. A split-face study design was performed for 6 sessions 2 weeks apart. Dermaroller was used for the right side, while dermapen was used for microneedling of the left side of the face with 2.5 mm long needles for both sides. Biopsy was taken from both sides before and at 2 weeks after last session. Each biopsy was stained with Hematoxylin and Eosin, Orcein, and Masson trichrome stains. There was significant improvement (p < .05) on both sides of the face when comparing after treatment to baseline. In spite of better clinical improvement observed on the dermaroller-treated side, however a non-significant difference was observed between both sides of the face (p = .618). Meanwhile, there was a better improvement on boxcar and rolling scars than that on icepick scars. In conclusion, microneedling showed significant clinical and histological improvement in the management of atrophic post-acne scars with no significant difference between using dermaroller or dermapen. The dermaroller session is more rapid as it covers a larger skin surface area, but with more pain and bleeding during the session than dermapen, and post-session erythema and edema are slightly more apparent after dermaroller.

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萎缩性面部痤疮疤痕;两种微针设备的双侧比较。
微针疗法是一种使用细针穿刺皮肤的微创疗法。本研究的目的是比较真皮轮与真皮针在治疗痤疮后萎缩性疤痕方面的临床疗效和组织学效果。该研究对 10 名痤疮后萎缩性疤痕患者进行了研究,采用分面研究设计,共进行了 6 次治疗,每次治疗间隔 2 周。右侧面部使用 Dermaroller,左侧面部使用 Dermapen,两侧面部均使用 2.5 毫米长的微针。在最后一次治疗前和治疗后两周,对两侧面部进行活检。每个活检组织都用苏木精和伊红、奥色素和马森三色染色。结果显示,治疗效果明显改善(p p = .618)。同时,箱车疤痕和滚动疤痕的改善效果优于冰锥疤痕。总之,微针疗法在治疗萎缩性痤疮后疤痕方面显示出明显的临床和组织学改善效果,使用 dermaroller 或 dermapen 没有明显差异。dermaroller治疗过程更迅速,因为它覆盖的皮肤表面积更大,但治疗过程中的疼痛和出血比dermapen更多,而且治疗后的红斑和水肿在dermaroller治疗后稍显明显。
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来源期刊
CiteScore
2.50
自引率
0.00%
发文量
36
审稿时长
>12 weeks
期刊介绍: A unique journal that focuses on the application of cosmetic laser and light therapies on the skin. The Journal of Cosmetic & Laser Therapy provides a forum for stimulating and up-to-date studies demonstrating the wide range of therapeutic options for clinicians and surgeons involved in cosmetic and dermatological treatment. The journal is aimed at dermatologists, cosmetic surgeons, plastic and facial plastic surgeons, oculoplastic surgeons and all those interested in the rapidly expanding field of cosmetic and laser therapy. Features include: -Cosmetic surgery, including facial rejuvenation, hair removal and skin resurfacing -Use of lasers and other light sources for cosmetic and dermatological treatment -Applications of peeling agents, fillers, injectables, implants and other cosmetic modalities -Topical treatments -Practical tips and safety issues
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