Journal of Cosmetic and Laser Therapy最新文献

Background: Low-level laser therapy (LLLT) at 675 nm, within the red light spectrum, has emerged as a noninvasive therapeutic option for various dermatological conditions, including aging-related skin changes, melasma, acne vulgaris, and striae distensae.

Aims: This review aims to elucidate the therapeutic potential of the 675 nm laser in dermatology by synthesizing existing research evidence and clinical outcomes.

Methods: A literature search was conducted on PubMed to include studies investigating the efficacy of the 675 nm laser in diverse dermatological conditions. Parameters such as treatment protocols, patient demographics, and outcome measures were analyzed to assess the laser's therapeutic associations. The literature search composed of clinical trials or review articles. Studies were additionally identified by searching reference lists of included articles. Only articles in English were utilized for this review.

Results: The 675 nm laser demonstrates efficacy in addressing aging-related skin changes, including facial rejuvenation and wrinkle reduction, with significant improvement observed in skin texture and collagen remodeling. Additionally, the laser exhibits promising outcomes in treating melasma and hyperpigmentation disorders, acne vulgaris, and striae distensae, offering selective damage to target tissues with minimal adverse effects.

Conclusions: The 675 nm laser presents a versatile and innovative therapeutic option in dermatology, offering noninvasive treatment modalities for various health and cosmetic concerns. Further research and clinical trials are warranted to optimize treatment protocols and fully elucidate its therapeutic potential in diverse patient populations.

Areolar Sebaceous Hyperplasia (ASH) consists of enlarged Montgomery tubercles, skin-colored papules in the peripheral border of the areola, formed by the openings of the ducts of Montgomery's glands. Treatment options are only briefly discussed in literature as it is mostly presented as asymptomatic or paucisymptomatic. However, this traditional standpoint does not take into consideration the psychological impact that it may have on the patient. We present a case of prominent Montgomery tubercles treated with CO2 laser with good response.

Both ablative fractional laser (AFL) and non-ablative fractional laser (NAFL) are gaining popularity in the treatment of atrophic acne scars. However, single NAFL may not be as effective as single AFL in clinical practice. This split-face and evaluator-blind study compared the efficacy and safety of multiple consecutive NAFL (1565 nm Er: glass laser) and a single AFL (10600 nm CO₂ laser) in the treatment of facial atrophic acne scars. 13 subjects with V, U and M-shape atrophic scars were treated with either NAFL group (once a month for 3 consecutive sessions of 1565 nm Er: glass laser) or AFL group (a single session of fractional CO₂ laser). We found that both AFL group and NAFL group showed decreased 4-point scale and ECCA scores for respective V, U, M types, but there was no statistically difference between the two groups. NAFL group showed lower pain score, less oozing and crusting, and shorter duration of the adverse effects as well. The average satisfaction score was higher in NAFL group, although there was no statistically significance. In conclusion, consecutive triple NAFL treatment could approach a single AFL treatment for atrophic acne scars, while NAFL treatment causes less pain and fewer adverse events.

Hyperpigmentation is a common dermatological condition characterized by the darkening of patches of skin compared to the surrounding areas. It can occur in individuals of all skin types and ethnicities, and is caused by an overproduction or accumulation of melanin, the pigment responsible for the color of our skin, hair, and eyes. This comprehensive overview aims to delve into the various types, causes, risk factors, clinical manifestations, diagnosis, and treatment options for hyperpigmentation. Additionally, it explores the global and national prevalence of hyperpigmentation, its etiology, pathophysiology and diagnosis and treatment strategies. Furthermore, examines the formulations and dosage forms used to treat hyperpigmentation, including their side effects. It also discusses combination drugs and their associated side effects, as well as novel drug delivery systems and nanocarriers employed in the treatment of hyperpigmentation, providing insight into future prospects in this field.

Background: The use of non-ablative fractionated lasers for skin rejuvenation has been proven to be effective in improving skin texture, and has become popular due to minimal wounding, significantly shorter recovery times and decreased adverse effects.

Objective: To retrospectively analyze improvement in skin texture in healthy women aged over 18 years with Fitzpatrick skin type II-IV.

Methods: Participants received 3 facial and/or neck treatments with the 1570-nm fractional scanning diode laser at one-month intervals. Three months after the last treatment session two blinded evaluators assessed skin improvement using before and after photos. Pain and patient satisfaction were recorded.

Results: Sixteen women with a mean age of 45.4 ± 4.1 years (range 35-50 years) and skin type II-IV were included in the analysis. All 16 participants received facial treatments and seven (43.8%) also received neck treatments. Three months follow-up evaluation showed that the majority of participants had at least a visible change in the treated areas. Mean pain score was low and decreased with each treatment session.

Conclusion: Skin treatment using fractional scanning 1570-nm diode laser improves skin laxity in women with skin types II-IV. Larger studies are warranted to further clarify the efficacy and safety of this modality.

Background: Autologous fat transplantation has gained increasing attention in the field of cosmetic surgery. However, a series of complications can occur after fat transplantation.

Case presentation: A 24-year-old woman presented at our Hospital with nasal skin necrosis and ulceration. She had undergone autologous fat transplantation on the nose six days ago. Physical examination showed an abnormal skin range of approximately 5 × 2 cm on the left side of the nose. The initial diagnosis was "skin necrosis after autologous fat grafting for augmentation rhinoplasty." In addition to the conventional treatment, topical oxygen therapy (TOT) and platelet-rich fibrin (PRF) injection were applied to the nasal wounds area. After 16 days, the pale and dark areas of necrosis on nose were scabby, and the local skin conditions were significantly improved.

Conclusion: We treated a case of ischemic necrosis of the skin after autologous fat grafting for augmentation rhinoplasty. For this kind of local vascular embolism, we first proposed a comprehensive therapy of "biological + physical + drug." The therapeutic method achieved satisfactory results, providing a new strategy for the clinical treatment of vascular embolism.

Granuloma faciale is a benign and rare skin disease, which usually presents as well-defined red-purple asymptomatic plaques or nodules on the face but can also present extra-facially. It poses a significant therapeutic challenge, with varying degrees of success reported by a range of medical and surgical treatments. We describe a 41-year-old lady with biopsy-confirmed facial granuloma faciale, affecting her nose, cheeks, upper lip, and forehead, who had failed a variety of medical treatments, UVB phototherapy, and pulsed dye laser. She was successfully treated with ablative fractional CO₂ laser, with a sustained response, without recurrence or complications maintained for 1 year.

Objective: The purpose of this study was to assess changes in skin elasticity and other skin defects related to the aging of skin around eyes following the use of combination treatment carboxytherapy and chemical peels (ferulic acid combined with ascorbic acid, lactobionic acid).

Material and methods: A total of 39 Caucasian patients were subjected to a series of five combination carboxytherapy and chemical peels treatments at weekly intervals. The Cutometer device was used to objectively measure skin elasticity. The assessment was supplemented by photographic documentation.

Results: A statistically significant improvement in skin elasticity assessed on the basis of R2 and R7 parameters (p < .0001, p = .001, respectively) was demonstrated after a series of five sessions of carboxytherapy combined with chemical peels. The improvement in the R2 parameter was observed in 82.1%, while R7 in 76.9% of study participants. It observed that the number of participants who benefited from treatment with ferulic acid and ascorbic acid was statistically higher compared with the second group (p = .036). Improved R2 values were reported in 100% of participants undergoing carboxytherapy combined with ferulic and ascorbic acid.

Conclusion: Carboxytherapy in combination with chemical peels improved skin elasticity and can be used to reduce other skin defects.

The high-frequency generator is considered a collagen stimulator and skin revitalizer, however there are few studies exploring its effects in the field of rejuvenation and aesthetics. Thus, this study aimed to investigate the impact of high frequency generator therapy on facial aging. A total of 26 participants aged between 50 and 60 years were selected and received high frequency generator treatment for eight weeks. The evaluation was conducted using a combination of photographic records and assessment tools, including Rosenberg scale, perception and satisfaction with treatment evaluation, overall aesthetic improvement scale, and modified Fitzpatrick scale. The analysis conducted by the Global Aesthetic Improvement Scale yielded significant results. The Modified Fitzpatrick Wrinkle Scale showed that high frequency therapy led to statistically significant improvements in the appearance of nasolabial wrinkles (right T0: 1.48, T8: 0.87; left T0: 1.51, T8: 1.05) and periorbital wrinkles (right T0: 1.69, T8: 1.05; left T0: 1.71, T8: 1.08). In conclusion, high frequency generator therapy can be a highly effective tool for treating skin aging on the face, however, we recommend that future research includes control groups, and adopts objective measures to expand knowledge about the effects of high frequency.

Background: Alopecia areata (AA) is a common autoimmune T-cell mediated non-scarring, form of hair loss. It affects people of all ages and sexes.

Aim: To compare the efficacy of intralesional vitamin D3 injection versus that of intralesional triamcinolone acetonide in the treatment of patchy alopecia areata.

Patients and methods: This clinical study was carried on 40 adult patients with patchy alopecia areata, the patients were categorized into two groups. Group I involved 20 patients who received 1 ml of intralesional injection of vitamin D3 (cholecalciferol aqueous preparation 200 000 IU/2 ml) every 4 weeks for a maximum of three sessions. Group II involved 20 patients who received 1 ml of intralesional injection of triamcinolone acetonide 40 mg/mL every 4 weeks for a maximum of three sessions. Clinical and trichoscopic evaluations were done at the baseline, each session and for 3 months after the last session.

Results: There was no statistically significant difference between the two studied groups regarding the degree of clinical improvement (p = .8). A statistically significant reduction in AA specific trichoscopic signs was detected at the end of the sessions and after 3 months of follow-up in both groups, without any statistically significant difference between them. Also a statistically significant difference was found between both groups regarding the reported adverse effects with a significant better patient satisfaction encountered toward the intralesional vitamin D3 injection.

Conclusion: Intralesional vitamin D3 is a promising effective, simple, safe, and inexpensive, therapeutic modality for patchy AA.