{"title":"Oxcarbazepine and clozapine interaction","authors":"Y. W. Francis Lam Pharm.D., FCCP","doi":"10.1002/pu.31251","DOIUrl":null,"url":null,"abstract":"<p>The atypical antipsychotic clozapine is considered the primary agent for patients with treatment-resistant schizophrenia, and is also used at times in the treatment of other treatment-resistant psychotic disorders. Despite its efficacy, use of clozapine is often limited by the occurrence of significant adverse effects, smoking-induced increased metabolism, and drug-drug interactions due to co-administered medications to treat concurrent medical and psychiatric conditions.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 1","pages":"2"},"PeriodicalIF":0.0000,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31251","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The atypical antipsychotic clozapine is considered the primary agent for patients with treatment-resistant schizophrenia, and is also used at times in the treatment of other treatment-resistant psychotic disorders. Despite its efficacy, use of clozapine is often limited by the occurrence of significant adverse effects, smoking-induced increased metabolism, and drug-drug interactions due to co-administered medications to treat concurrent medical and psychiatric conditions.
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