Experiences and perspectives on rapid-test diagnosis of tuberculosis, histoplasmosis and cryptococcosis in people with advanced HIV/AIDS disease in Porto Alegre, Brazil.

IF 2.9 3区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES PLoS ONE Pub Date : 2024-11-27 eCollection Date: 2024-01-01 DOI:10.1371/journal.pone.0312204
Angelo Brandelli Costa, Laura Dos Santos Boeira, Damião Soares de Almeida-Segundo, Lara Wiehe Chaves, Laura Sainz, Larissa Silva, Leonardo Mello Garcia Dos Santos, Nicole Reis, Alessandro C Pasqualotto, Omar Sued, Freddy Perez
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Abstract

The rapid diagnosis of opportunistic infections (OIs) is critical for improving the health outcomes of people living with HIV/AIDS (PLWHA). This study aimed to describe the feasibility of implementing a package for the rapid diagnosis of tuberculosis, histoplasmosis, and cryptococcosis in patients with advanced HIV/AIDS disease in Porto Alegre, Brazil. The research involved two focus groups with health professionals, four in-depth interviews with healthcare managers, and twelve interviews with PLWHA. The corpus was analyzed using Descending Hierarchical Classification (DHC). The study found that the rapid test diagnosis intervention was generally well-received by patients and health professionals, improving diagnosis and treatment outcomes. However, it also identified several areas for improvement, including the need for expanded psychosocial support and enhanced coordination between health services. The findings have important implications for the development and implementation of policies and programs aimed at enhancing the diagnosis and treatment of OIs among PLWHA with advanced diseases. Further research should explore social determinants of HIV/AIDS mortality to offer valuable insights into improving prevention and treatment strategies. By prioritizing patient-centered care and improving coordination between health services, policymakers and health professionals can improve the health outcomes of PLWHA with advanced disease in Porto Alegre and other similar settings.

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巴西阿雷格里港晚期艾滋病毒/艾滋病患者结核病、组织胞浆菌病和隐球菌病快速检测诊断的经验和观点。
机会性感染 (OI) 的快速诊断对于改善艾滋病毒/艾滋病感染者 (PLWHA) 的健康状况至关重要。本研究旨在描述在巴西阿雷格里港实施快速诊断晚期艾滋病患者中结核病、组织胞浆菌病和隐球菌病的一揽子方案的可行性。研究包括与医疗专业人员进行的两次焦点小组讨论、与医疗管理人员进行的四次深入访谈以及与艾滋病毒/艾滋病晚期患者进行的十二次访谈。语料库采用降序分级法(DHC)进行分析。研究发现,快速检测诊断干预措施受到了患者和医疗专业人员的普遍欢迎,提高了诊断和治疗效果。不过,研究也发现了几个需要改进的方面,包括需要扩大心理支持和加强医疗服务之间的协调。这些研究结果对制定和实施旨在加强晚期 PLWHA 中 OIs 诊断和治疗的政策和计划具有重要意义。进一步的研究应探讨艾滋病毒/艾滋病死亡率的社会决定因素,为改进预防和治疗策略提供有价值的见解。通过优先考虑以患者为中心的护理和改善医疗服务之间的协调,政策制定者和医疗专业人员可以改善阿雷格里港和其他类似地区晚期艾滋病感染者的健康状况。
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来源期刊
PLoS ONE
PLoS ONE 生物-生物学
CiteScore
6.20
自引率
5.40%
发文量
14242
审稿时长
3.7 months
期刊介绍: PLOS ONE is an international, peer-reviewed, open-access, online publication. PLOS ONE welcomes reports on primary research from any scientific discipline. It provides: * Open-access—freely accessible online, authors retain copyright * Fast publication times * Peer review by expert, practicing researchers * Post-publication tools to indicate quality and impact * Community-based dialogue on articles * Worldwide media coverage
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