Anhedonia in flux: Understanding the associations of emotion regulation and anxiety with anhedonia dynamics in a sample with major depressive disorder.

IF 4.9 2区 医学 Q1 CLINICAL NEUROLOGY Journal of affective disorders Pub Date : 2024-11-25 DOI:10.1016/j.jad.2024.11.059
Michael R Gallagher, Amanda C Collins, Damien Lekkas, Matthew D Nemesure, Tess Z Griffin, George D Price, Michael V Heinz, Arvind Pillai, Subigya Nepal, Daniel M Mackin, Andrew T Campbell, E Samuel Winer, Nicholas C Jacobson
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Abstract

Negative rumination and emotion regulation difficulties have been consistently linked with depression. Despite anhedonia-the lack of interest in pleasurable experiences-being a cardinal symptom of depression, emotion regulation of positive emotions, including dampening, are considered far less in the literature. Given that anhedonia may manifest through blunted responses to previously positive or enjoyable experiences, it is vital to understand how different positive emotion regulation strategies impact anhedonia symptom severity and how it can vary or change over time. Moreover, understanding the detrimental or protective nature of positive emotion regulation on anhedonia can aid with future anhedonia-focused treatments. Therefore, the current study examined the temporal association between anhedonia dynamics and two different emotion rumination strategies in response to positive emotions: dampening and positive rumination. Depressed persons (N = 137) completed baseline measures of positive emotion regulation, difficulties regulating negative emotions, and anxiety, and completed ecological momentary assessments three times per day for 90 days regarding their depressive symptoms, including anhedonia. We assessed baseline dampening and amplifying scores to predict anhedonia dynamics through four linear models with interactions. Providing partial support for our hypotheses, results indicate that amplifying positivity is positively associated with fluctuations, instability, and acute changes in anhedonia over the course of 90 days; however, neither dampening, difficulties regulating negative emotions, nor anxiety were related to anhedonia dynamics. The current findings suggest that amplifying positivity may be able to predict changes in anhedonia over time and should further be examined as a potential protective factor of anhedonia.

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变化中的失乐症:了解重度抑郁障碍样本中情绪调节和焦虑与失乐动态的关联。
消极反刍和情绪调节困难一直与抑郁症有关。尽管失乐症--对愉悦的体验缺乏兴趣--是抑郁症的主要症状,但包括抑制在内的积极情绪调节在文献中却鲜有提及。鉴于失乐症可能表现为对之前积极或愉快经历的反应迟钝,因此了解不同的积极情绪调节策略如何影响失乐症症状的严重程度,以及失乐症症状如何随着时间的推移而变化至关重要。此外,了解积极情绪调节对失乐症的有害性或保护性,有助于未来以失乐症为重点的治疗。因此,本研究考察了失乐症的动态变化与两种不同的情绪反刍策略之间的时间关联:抑制和积极反刍。抑郁症患者(N = 137)完成了积极情绪调节、消极情绪调节困难和焦虑的基线测量,并在90天内每天三次完成了有关抑郁症状(包括失乐症)的生态瞬间评估。我们评估了基线抑制和放大得分,通过四个线性模型和交互作用来预测失乐症的动态变化。结果表明,在 90 天内,积极性放大与失乐症的波动、不稳定性和急性变化呈正相关,这为我们的假设提供了部分支持;然而,抑制、调节负面情绪的困难或焦虑都与失乐症的动态变化无关。目前的研究结果表明,放大积极性可能能够预测失乐症随着时间的推移而发生的变化,并应将其作为失乐症的潜在保护因素加以进一步研究。
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来源期刊
Journal of affective disorders
Journal of affective disorders 医学-精神病学
CiteScore
10.90
自引率
6.10%
发文量
1319
审稿时长
9.3 weeks
期刊介绍: The Journal of Affective Disorders publishes papers concerned with affective disorders in the widest sense: depression, mania, mood spectrum, emotions and personality, anxiety and stress. It is interdisciplinary and aims to bring together different approaches for a diverse readership. Top quality papers will be accepted dealing with any aspect of affective disorders, including neuroimaging, cognitive neurosciences, genetics, molecular biology, experimental and clinical neurosciences, pharmacology, neuroimmunoendocrinology, intervention and treatment trials.
期刊最新文献
Association between body fat percentage and depression: A cross-sectional study of NHANES Editorial Board Anhedonia in flux: Understanding the associations of emotion regulation and anxiety with anhedonia dynamics in a sample with major depressive disorder. Blood cytokines in major depressive disorder in drug-naïve adolescents: A systematic review and meta-analysis. Multiple pathways to suicide: A network analysis based on three components of psychological pain.
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