Knowledge, Attitudes, Practices on Antimicrobial Use in Animals Among Livestock Sector Stakeholders in Kenya.

Abstract

Background: Antimicrobials are used on farms to manage livestock diseases. In many developing countries, antimicrobial use (AMU) is insufficiently controlled, and antimicrobials are prone to misuse and abuse, thereby fostering the emergence of antimicrobial resistance (AMR). AMR remains a challenge in Kenya, and the extent remains unknown. This study assessed the knowledge, attitudes, and practices (KAP) regarding AMU among multisectoral stakeholders in Kenya. Methods: The cross-sectional survey was conducted in August 2021 among 381 livestock farmers in Busia, Nakuru, and Isiolo Counties, while 47 animal health service providers (AHSPs) and 32 One Health practitioners (OHPs) were enrolled across Kenya. The data collection tool uploaded on KoBoCollect software was used to collect information on demographics, farming systems, KAP on AMR and AMU, and sources of information. Descriptive statistics were performed. Knowledge was either correct or incorrect, while practices were assigned as desirable or undesirable. Bivariable analysis to assess factors associated with KAP using odds ratio (OR) at 95% confidence level (CL). The Pearson correlation test was conducted to test the correlation between demographic independent variables and farmers' KAP, p < 0.05. Results: Most farmers, 234 (61.4%), were young adults between 30 and 49 years old. Additionally, 48.9% of the farmers had less than 5 years of experience in farming. Among the AHSPs, 76.6% were male, with 21 (44.7%) having 2-5 years of experience. All (32) OHPs had over 15 years of experience. Correct knowledge in AMR/AMU was observed in 52.6% of the farmers, 88.2% of AHSPs, and all OHPs. Desirable practices were observed in 133 (34.9%) of farmers, 22 (45.1%) of AHSPs, and 25 (76.4%) of OHPs. Among the farmers, having basic education was associated with correct knowledge (OR 4.07, p=0.0007); however, being male (OR 1.584, p=0.0456) and having a higher education level (OR 1.582, p=0.0165) were associated with desirable practices. There was a significant positive correlation between having correct knowledge and level of education (p < 0.0001), years of farming, and correct knowledge (p < 0.0001). However, years of farming negatively correlated with the desirable practices (p < 0.0001). Farmers' preferred sources of information regarding AMR/AMU were friends 130 (33.9%), farmer meetings/workshops 99 (25.9%), and radio 41 (10.7%). AHSPs obtain information from scientific conferences/trainings (17) (65.4%), workshops (13) (50.0%), and TV and radio (12) (46.2%), while OHSPs mostly get information through college training (14) (58.3%) and workshops (8) (33.3%). Conclusion: Correct knowledge of AMR/AMU did not result in adopting the desirable practices. A better understanding of the socioeconomic aspects of welfare, good livestock production measures, and AMU stewardship will be desired. This study provides a foundation for developing effective antimicrobial stewardship, best farm practices, and intervention programs to reduce inappropriate AMU. Public Implication: Farmers' AHSP practices are likely to promote the emergence of AMR, a health challenge for animals and humans.