{"title":"Creutzfeldt–Jakob disease: A case report","authors":"Fahad Rasool Butt HBSc , Thanansayan Dhivagaran HBSc , Syed Naqvi MD, FRCPC, DABR","doi":"10.1016/j.radcr.2024.11.011","DOIUrl":null,"url":null,"abstract":"<div><div>Creutzfeldt–Jakob Disease (CJD) is a rare, fatal neurodegenerative disorder that is caused by prion proteins. Patients often present with rapidly progressive dementia, ataxia, myoclonus, memory impairment, visual problems, and changes in personality. In this case report, we aimed to address the course of a 62 year old female who presented with progressive decline in cognitive function and died within 6 months of presentation. The patient underwent cerebrospinal fluid testing, MRI brain, and electroencephalography during her stay in the hospital. Ultimately, an autopsy was performed, which demonstrated spongiform changes, neuronal loss, and astrogliosis, consistent with CJD.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 2","pages":"Pages 1095-1098"},"PeriodicalIF":0.0000,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1930043324012780","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Creutzfeldt–Jakob Disease (CJD) is a rare, fatal neurodegenerative disorder that is caused by prion proteins. Patients often present with rapidly progressive dementia, ataxia, myoclonus, memory impairment, visual problems, and changes in personality. In this case report, we aimed to address the course of a 62 year old female who presented with progressive decline in cognitive function and died within 6 months of presentation. The patient underwent cerebrospinal fluid testing, MRI brain, and electroencephalography during her stay in the hospital. Ultimately, an autopsy was performed, which demonstrated spongiform changes, neuronal loss, and astrogliosis, consistent with CJD.
期刊介绍：
The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.
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