Advancements in Biological Conversion of C1 Feedstocks: Sustainable Bioproduction and Environmental Solutions.

IF 3.9 2区生物学 Q1 BIOCHEMICAL RESEARCH METHODS ACS Synthetic Biology Pub Date : 2024-12-20 Epub Date: 2024-11-29 DOI:10.1021/acssynbio.4c00519

Wooyoung Park, Seungwoo Cha, Ji-Sook Hahn

引用次数: 0

Abstract

The use of one-carbon (C1) feedstocks, including carbon dioxide (CO₂), carbon monoxide (CO), formate (HCO₂H), methanol (CH₃OH), and methane (CH₄), presents a significant opportunity for sustainable bioproduction and environmental conservation. This Perspective explores the development of biological methods for converting C1 feedstocks into valuable products, emphasizing major progress from engineering native C1 assimilation pathways to the creation of synthetic autotrophs and methylotrophs that utilize these carbon sources. Additionally, we discuss hybrid approaches that merge biological and electrochemical systems, particularly for the conversion of CO₂. This Perspective underscores the importance of C1 bioconversion in promoting sustainable biotechnological strategies for a low-carbon future.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

C1原料生物转化的进展：可持续的生物生产和环境解决方案。

使用一碳（C1）原料，包括二氧化碳（CO2）、一氧化碳（CO）、甲酸酯（HCO2H）、甲醇（CH3OH）和甲烷（CH4），为可持续生物生产和环境保护提供了重要机会。本展望探讨了将C1原料转化为有价值产品的生物方法的发展，强调了从工程天然C1同化途径到利用这些碳源合成自养生物和甲基养生物的主要进展。此外，我们还讨论了融合生物和电化学系统的混合方法，特别是二氧化碳的转化。该展望强调了C1生物转化在促进可持续生物技术战略以实现低碳未来方面的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

ACS Synthetic Biology 生物-

CiteScore

8.00

自引率

10.60%

发文量

380

审稿时长

6-12 weeks

期刊介绍： The journal is particularly interested in studies on the design and synthesis of new genetic circuits and gene products; computational methods in the design of systems; and integrative applied approaches to understanding disease and metabolism. Topics may include, but are not limited to: Design and optimization of genetic systems Genetic circuit design and their principles for their organization into programs Computational methods to aid the design of genetic systems Experimental methods to quantify genetic parts, circuits, and metabolic fluxes Genetic parts libraries: their creation, analysis, and ontological representation Protein engineering including computational design Metabolic engineering and cellular manufacturing, including biomass conversion Natural product access, engineering, and production Creative and innovative applications of cellular programming Medical applications, tissue engineering, and the programming of therapeutic cells Minimal cell design and construction Genomics and genome replacement strategies Viral engineering Automated and robotic assembly platforms for synthetic biology DNA synthesis methodologies Metagenomics and synthetic metagenomic analysis Bioinformatics applied to gene discovery, chemoinformatics, and pathway construction Gene optimization Methods for genome-scale measurements of transcription and metabolomics Systems biology and methods to integrate multiple data sources in vitro and cell-free synthetic biology and molecular programming Nucleic acid engineering.