Dosimetric advantages of dual arc increments for head and neck volumetric-modulated arc therapy in the Monaco treatment planning system.

IF 2 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of Applied Clinical Medical Physics Pub Date : 2024-11-29 DOI:10.1002/acm2.14571
Jin Hwa Choi, Hyejo Ryu, Do Hoon Oh, Lee Yoo, Minsoo Chun
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Abstract

Purpose: This study aimed to assess the dosimetric advantages of dual arc increments in head and neck volumetric-modulated arc therapy (VMAT) in the Monaco treatment planning system (TPS).

Methods: Three VMAT plans were created for each of the 10 patients by prescribing 70 Gy in 35 fractions with arc increment combinations of 30°/30°, 15°/15°, and 30°/15° in the Monaco TPS. The dose to 0.03 cm3 volume (D0.03cc), conformity number, and homogeneity and gradient indices was compared for the planning target volume (PTV), and the D0.03cc and mean dose (Dmean) of the spinal cord, brain stem, parotid glands were compared. For plan complexity evaluation, the monitor unit and various related metrics were compared. Wilcoxon signed-rank tests were performed across plans for the evaluated indicators.

Results: For PTV, plans with 30°/15° showed comparable D0.03cc and homogeneity and gradient indices to those of plans with 30°/30° and 15°/15° while exhibiting a better conformity number. The D0.03cc for spinal cord and brain stem for plans with 30°/15° were 26.0% and 20.8% less than those with 30°/30° and 16.8% and 19.0% less than those with 15°/15°, respectively. The Dmean for the left and right parotid glands under plans with 30°/15° were 17.4% and 13.2% less than those with 30°/30° and 14.0% and 9.8% less than those with 15°/15°, respectively. The total monitor unit in plans with 30°/15° was less than that in other plans but with no significance. The plans with 30°/15° showed higher modulation complexity and plan-averaged irregularity, while no significant differences observed in both plan-averaged area and modulation compared with other plans.

Conclusion: In head and neck VMAT, a dual arc increment of 30°/15° seems advisable because it can substantially reduce doses to normal tissues with comparable delivery efficiency while maintaining target dose coverage.

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在摩纳哥治疗计划系统中,头颈部体积调节电弧治疗双弧增量的剂量学优势。
目的:本研究旨在评估摩纳哥治疗计划系统(TPS)中头颈部体积调节电弧治疗(VMAT)双弧增量的剂量学优势。方法:在Monaco TPS中,以30°/30°、15°/15°和30°/15°的弧度增量组合,将70 Gy分为35个分数,为10例患者每人创建3个VMAT计划。比较计划靶体积(PTV)的0.03 cm3体积剂量(D0.03cc)、符合数、均匀性和梯度指标,比较脊髓、脑干、腮腺的D0.03cc和平均剂量(Dmean)。对于计划复杂性评估,比较了监控单元和各种相关指标。对评估指标在各计划间进行Wilcoxon sign -rank检验。结果:对于PTV, 30°/15°平面与30°/30°和15°/15°平面的D0.03cc、均匀性和梯度指数相当,但符合度更好。30°/15°方案脊髓和脑干的D0.03cc分别比30°/30°方案低26.0%和20.8%,比15°/15°方案低16.8%和19.0%。30°/15°方案下左右腮腺的Dmean分别比30°/30°方案低17.4%和13.2%,比15°/15°方案低14.0%和9.8%。30°/15°方案的总监测单位数少于其他方案,但差异无统计学意义。30°/15°方案的调制复杂性和平面平均不规则性更高,而平面平均面积和调制方式与其他方案相比无显著差异。结论:在头颈部VMAT中,30°/15°的双弧增量似乎是可取的,因为它可以在保持靶剂量覆盖的同时,在相当的递送效率下大大减少对正常组织的剂量。
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来源期刊
CiteScore
3.60
自引率
19.00%
发文量
331
审稿时长
3 months
期刊介绍: Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission. JACMP will publish: -Original Contributions: Peer-reviewed, investigations that represent new and significant contributions to the field. Recommended word count: up to 7500. -Review Articles: Reviews of major areas or sub-areas in the field of clinical medical physics. These articles may be of any length and are peer reviewed. -Technical Notes: These should be no longer than 3000 words, including key references. -Letters to the Editor: Comments on papers published in JACMP or on any other matters of interest to clinical medical physics. These should not be more than 1250 (including the literature) and their publication is only based on the decision of the editor, who occasionally asks experts on the merit of the contents. -Book Reviews: The editorial office solicits Book Reviews. -Announcements of Forthcoming Meetings: The Editor may provide notice of forthcoming meetings, course offerings, and other events relevant to clinical medical physics. -Parallel Opposed Editorial: We welcome topics relevant to clinical practice and medical physics profession. The contents can be controversial debate or opposed aspects of an issue. One author argues for the position and the other against. Each side of the debate contains an opening statement up to 800 words, followed by a rebuttal up to 500 words. Readers interested in participating in this series should contact the moderator with a proposed title and a short description of the topic
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