Anemia secondary to copper deficiency in a child receiving gastrojejunal feeds: A case report.

JPGN reports Pub Date : 2024-09-05 eCollection Date: 2024-11-01 DOI:10.1002/jpr3.12129
Sarah Sabir, Megha Jain, Meenakshi Goyal, Jonathan E Teitelbaum, Katelyn Guli
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Abstract

Pediatric macrocytic anemia has a varied etiology, including nutritional deficiencies, such as folate or B12 deficiency, hematological factors, and micronutrient deficiencies, such as copper deficiency. We present the case of a 9-year-old girl with a complex medical history and gastrojejunal tube (G-J tube)-dependent nutrition who developed macrocytic anemia due to copper deficiency. Despite receiving enteral nutrition, her dietary copper intake was insufficient, leading to hematological abnormalities. Copper supplementation resulted in the normalization of hematological indices, highlighting the importance of considering trace element deficiencies in patients reliant on enteral nutrition, particularly in those receiving jejunal feeds. This case underscores the necessity for vigilant monitoring and optimized micronutrient supplementation in such patients given the lack of standardized guidelines for copper supplementation.

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接受胃空肠喂养的儿童继发性缺铜贫血:1例报告。
儿童大细胞性贫血有多种病因,包括营养缺乏,如叶酸或B12缺乏,血液因素,和微量营养素缺乏,如铜缺乏。我们提出的情况下,一个9岁的女孩复杂的病史和胃空肠管(G-J管)依赖营养谁发展大细胞性贫血,由于缺铜。尽管接受了肠内营养,但她的膳食铜摄入量不足,导致血液系统异常。补充铜导致血液学指标正常化,强调了考虑依赖肠内营养的患者微量元素缺乏的重要性,特别是那些接受空肠喂养的患者。该病例强调了在缺乏铜补充标准指南的情况下,对此类患者进行警惕监测和优化微量营养素补充的必要性。
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