Time to Reach Stone-free Status in Children Undergoing Retrograde Intrarenal Surgery.

IF 1.5 4区 医学 Q3 UROLOGY & NEPHROLOGY Urology Journal Pub Date : 2025-01-12 DOI:10.22037/uj.v21i.8270
Süleyman Tagcı, Gökhan Demirtaş, Bilge Karabulut, Hüseyin Tugrul Tiryaki
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Abstract

Purpose: Retrograde intrarenal surgery has become increasingly popular for renal stone disease but has very different stone-free rates in children. There is insufficient data in the literature regarding how long it takes to reach a stone-free status in children after retrograde intrarenal surgery. We aimed to evaluate the time to reach stone-free status and stone-free rates (SFR) in children who underwent retrograde intrarenal surgery.

Materials and methods: This retrospective study included children who had undergone retrograde intrarenal surgery. Ultrasonography was performed three months after the procedures for 18 months to evaluate stone clearance. We analyzed the stone-free rate and time to reach stone-free status.

Results: One hundred and five patients (mean age 6.66 + 5.27 years) were evaluated. Fifteen patients had staghorn stones, 31 had multiple stones, and 44 had single stones. The median follow-up period was 29 months (9-44 months) Of the 90 patients who underwent RIRS as the first treatment option, 38 (42.2%) achieved stone-free status with a single procedure, while 30 (33.3%) required repeat RIRS and other procedures.The stone-free rate was achieved in 75.5% of the patients in a mean of 12.25+40.19 months, In the group with staghorn stones, stone-free status was achieved in 4-36 months with a mean of 16.85+12.03 months, in patients with multiple stones in 2-41 months with a mean of 12.72+10.03 months, and in patients with single stones in 1-36 months with a mean of 10.23+9.10 months. Although the staghorn group achieved stone-free time for longer than the other two groups, there was no significant relationship between the three groups (P = .131) and achieved stone-free time.

Conclusion: A stone-free status can be achieved in children 12 months after retrograde intrarenal surgery. Since stone-free status is achieved over a long period, patient follow-ups should be planned accordingly, and there should be no rush to perform additional interventions in asymptomatic cases with residual stones.

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行逆行肾内手术儿童达到无结石状态的时间。
目的:逆行肾内手术治疗肾结石越来越流行,但儿童无结石率却大不相同。关于儿童逆行肾内手术后达到无结石状态需要多长时间,文献资料不足。我们的目的是评估接受逆行肾内手术的儿童达到无结石状态的时间和无结石率(SFR)。材料和方法:本回顾性研究纳入了行逆行肾内手术的儿童。术后3个月超声检查结石清除情况,随访18个月。我们分析了脱石率和达到脱石状态的时间。结果:共纳入105例患者,平均年龄6.66 + 5.27岁。15例为鹿角结石,31例为多发结石,44例为单发结石。中位随访时间为29个月(9-44个月)。在接受RIRS作为第一种治疗方案的90例患者中,38例(42.2%)通过一次手术达到无结石状态,而30例(33.3%)需要重复RIRS和其他手术。75.5%的患者达到无结石状态,平均为12.25+40.19个月;鹿角结石组4-36个月达到无结石状态,平均为16.85+12.03个月;多发性结石组2-41个月,平均为12.72+10.03个月;单一结石组1-36个月,平均为10.23+9.10个月。虽然鹿角组的无结石时间比其他两组长,但三组之间无显著相关性(P = 0.131)。结论:儿童逆行肾内手术后12个月可达到无结石状态。由于无结石状态需要很长一段时间才能达到,因此应相应地计划患者随访,对于无症状的结石残留病例,不应急于进行额外的干预。
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来源期刊
Urology Journal
Urology Journal UROLOGY & NEPHROLOGY-
CiteScore
2.60
自引率
6.70%
发文量
44
审稿时长
6-12 weeks
期刊介绍: As the official journal of the Urology and Nephrology Research Center (UNRC) and the Iranian Urological Association (IUA), Urology Journal is a comprehensive digest of useful information on modern urology. Emphasis is on practical information that reflects the latest diagnostic and treatment techniques. Our objectives are to provide an exceptional source of current and clinically relevant research in the discipline of urology, to reflect the scientific work and progress of our colleagues, and to present the articles in a logical, timely, and concise format that meets the diverse needs of today’s urologist. Urology Journal publishes manuscripts on urology and kidney transplantation, all of which undergo extensive peer review by recognized authorities in the field prior to their acceptance for publication. Accordingly, original articles, case reports, and letters to editor are encouraged.
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