A manganese phthalocyanine histidine composite-modified carbon paste electrode as a biomimetic sensor for bisphenol A determination

Abstract

A biomimetic sensor was prepared from carbon paste electrode (CPE) modified with manganese phthalocyanine (MnPc) and histidine (His), and used for the determination of bisphenol A (BPA). The electrochemical biomimetic sensor (MnPc-His-CPE) gave significant current responses for BPA oxidation in comparison with CPE and MnPc-CPE, individually. The morphological and chemical characterizations of the sensor surface were studied by FT-IR, UV-visible Spectrophotometry, and SEM. The electrochemical behavior of the sensor and the oxidation behavior of BPA at the MnPc-His-CPE/BPA interface were investigated by cyclic voltammetry (CV), chronocoulometry (CC), square wave voltammetry (SWV), and electrochemical impedance spectroscopy (EIS). Square wave voltammetry (SWV), applied as a sensitive analytical method for BPA determination, led to a good linear correlation between BPA concentration and peak current in the range from 2.10⁻⁸ mol.L⁻¹ to 5.10⁻⁵ mol.L⁻¹ and a detection limit of 4.63 nM (S/N = 3). The relative standard deviation was 4.10 % (n = 10). The proposed sensor was found to be highly selective for BPA. In addition, the reproducibility and stability of the sensor were found to be satisfactory. The accuracy of the electrochemical biomimetic sensor was compared with HPLC method. The sensor has been successfully applied for the determination of BPA from real water samples with a good recovery, ranging from 91.40 % to 106.30 %.