Cu-curcumin nanozyme for detection of Cr(vi) through an off–on strategy based on peroxidase mimicking activity †

IF 3.6 3区 化学 Q2 CHEMISTRY, ANALYTICAL Analyst Pub Date : 2024-12-02 DOI:10.1039/D4AN01358A
Ziwei Chai, Aifang Zhou, Jingjing Huang, Lingbo Qu, Jia Ge, Lin Zhang and Zhaohui Li
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Abstract

Hexavalent chromium ions (Cr(VI)) possess inherent toxicity and propensity for bioaccumulation in the environment. Herein, a Cu-curcumin nanozyme was synthesized via a one-pot solvothermal method. Based on the high peroxidase-like activity of the Cu-curcumin nanozyme, a novel and economical colorimetric platform has been developed for Cr(VI) assay. In the presence of hydrogen peroxide (H2O2), the Cu-curcumin nanozyme can catalyze the transformation of colorless 3,3′,5,5′-tetramethylbenzidine (TMB) into the blue product oxTMB. 8-Hydroxyquinoline (8-HQ) can inhibit the catalysis of the Cu-curcumin/TMB/H2O2 system, causing the blue color to fade. With the addition of Cr(VI), the peroxidase-like activity of the Cu-curcumin nanozyme is increased significantly, leading to the restoration of the Cu-curcumin/TMB/H2O2 system color. After optimization of the experimental parameters, a novel colorimetric sensor for Cr(VI) assay has been successfully developed with a low limit of detection (LOD) of 31.5 nM, affirming its potential for accurate Cr(VI) quantification in environmental specimens. In addition, paper strips integrated with a smartphone platform enhance the versatility and portability of the Cr(VI) assay, achieving an LOD of 0.1 μM.

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铜-姜黄素纳米酶通过过氧化物酶模拟活性的关闭策略检测Cr(Ⅵ)
六价铬离子(Cr(VI))在自然环境中具有固有的毒性和生物蓄积倾向。本文采用一锅溶剂热法合成了铜姜黄素纳米酶。由于cu -姜黄素纳米酶具有较高的过氧化物酶样活性,建立了一种新型的经济比色分析平台。在过氧化氢(H2O2)存在下,cu -姜黄素纳米酶能催化无色的3,3',5,5'-四甲基联苯胺(TMB)生成蓝色产物oxTMB。8-羟基喹啉(8-HQ)可以抑制cu -姜黄素/TMB/H2O2体系的催化作用,导致蓝色褪色。随着Cr(VI)的加入,cu -姜黄素纳米酶的过氧化物酶样活性被明显点亮,导致cu -姜黄素/TMB/H2O2体系的体系颜色恢复。通过对实验参数的优化,成功研制了一种新型的Cr(VI)比色传感器,其低检出限为31.5 nM,证实了其在环境样品中准确定量Cr(VI)的潜力。此外,与智能手机平台集成的试纸条增强了Cr(VI)测定的通用性和便携性,LOD可达0.1 μM。
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来源期刊
Analyst
Analyst 化学-分析化学
CiteScore
7.80
自引率
4.80%
发文量
636
审稿时长
1.9 months
期刊介绍: "Analyst" journal is the home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences.
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