Comprehensive Targeted and Quantitative Profiling of the Human Milk Metabolome: Impact of Delivery Mode, Breastfeeding Practices, and Maternal Diet

IF 4.5 2区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY Molecular Nutrition & Food Research Pub Date : 2024-12-01 DOI:10.1002/mnfr.202400424
Joaquim Calvo-Lerma, Raúl Cabrera-Rubio, Carles Lerin, Sonia González, Marta Selma-Royo, Cecilia Martínez-Costa, Teodoro Bottiglieri, Maria Carmen Collado
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Abstract

Human milk (HM) is rich in bioactive compounds and essential nutrients. While research has focused on lipids, minerals, immune markers, microbiota, and oligosaccharides, specific metabolites are less studied. This study uses targeted metabolomics to identify and quantify metabolites in HM and explores the impact of perinatal and dietary factors on the metabolomic profile.

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人乳代谢组的全面定向和定量分析:分娩方式、母乳喂养习惯和母亲饮食的影响
人乳(HM)富含生物活性化合物和必需营养素。虽然研究主要集中在脂质、矿物质、免疫标记物、微生物群和低聚糖上,但对特定代谢物的研究较少。本研究使用靶向代谢组学来鉴定和量化HM中的代谢物,并探讨围产期和饮食因素对代谢组学谱的影响。
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来源期刊
Molecular Nutrition & Food Research
Molecular Nutrition & Food Research 工程技术-食品科技
CiteScore
8.70
自引率
1.90%
发文量
250
审稿时长
1.7 months
期刊介绍: Molecular Nutrition & Food Research is a primary research journal devoted to health, safety and all aspects of molecular nutrition such as nutritional biochemistry, nutrigenomics and metabolomics aiming to link the information arising from related disciplines: Bioactivity: Nutritional and medical effects of food constituents including bioavailability and kinetics. Immunology: Understanding the interactions of food and the immune system. Microbiology: Food spoilage, food pathogens, chemical and physical approaches of fermented foods and novel microbial processes. Chemistry: Isolation and analysis of bioactive food ingredients while considering environmental aspects.
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