{"title":"A fight against cancer with advancement of Schiff base metal complexes: Future prospects","authors":"Monika Tyagi, Monika Dubey","doi":"10.1016/j.oor.2024.100692","DOIUrl":null,"url":null,"abstract":"<div><div>Cancer remains a formidable global health challenge, demanding continuous efforts to develop innovative and effective therapeutic strategies. Recently, Schiff base metal complexes (SBMCs) have attracted considerable interest as potential anticancer agents because of their varied chemical properties and promising biological activities. This comprehensive review delves the latest advancements in the use of SBMCs in cancer therapy. It covers the synthesis and characterization of these complexes, their mechanisms of action, and their potential advantages over conventional chemotherapy. Furthermore, the review discusses challenges and future perspectives in utilizing SBMCs to enhance cancer treatment outcomes, paving the way for a more targeted and personalized approach in the fight against cancer.</div></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"13 ","pages":"Article 100692"},"PeriodicalIF":0.0000,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Oncology Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772906024005387","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Cancer remains a formidable global health challenge, demanding continuous efforts to develop innovative and effective therapeutic strategies. Recently, Schiff base metal complexes (SBMCs) have attracted considerable interest as potential anticancer agents because of their varied chemical properties and promising biological activities. This comprehensive review delves the latest advancements in the use of SBMCs in cancer therapy. It covers the synthesis and characterization of these complexes, their mechanisms of action, and their potential advantages over conventional chemotherapy. Furthermore, the review discusses challenges and future perspectives in utilizing SBMCs to enhance cancer treatment outcomes, paving the way for a more targeted and personalized approach in the fight against cancer.
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