Clinical outcomes of hospitalised COVID-19 Omicron patients treated with traditional Chinese Medicine: A Retrospective Studymedicine: a retrospective study of a large medical centre in Shanghai, China

IF 2.2 4区 医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE Journal of Herbal Medicine Pub Date : 2024-12-01 DOI:10.1016/j.hermed.2024.100971
Yafang Guo , Hong Lu , Jialin Zhu , Jianjun Feng , Yonggang Gu , Li Ma , Yunsheng Huang , Chengxing Xu , Xinge Feng , Zhongqiu Wen , Lili Gao , Wujun Xiong , Xuhui Bao , Changming Zhang , Yipeng Zeng
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Abstract

Introduction

The efficacy of Chinese herbal medicine (CHM) in treating infection with the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains to be investigated. This study aimed to assess the efficacy of CHM in COVID-19 Omicron patients.

Methods

Inpatients aged 18 years or older were divided into two groups based on their treatment: Western medicine group (WMG) and CHM group (CHMG). Demographic and COVID-19-related outcome data of the inpatients were collected. We analyzed negative conversion time, hospital stay, and clinical outcomes.

Results

The Asymptomatic Type: Negative conversion time significantly decreased in the CHMG compared with that in the WMG (3.0 [range: 2.0–7.0] days vs 5.0 [range: 3.0–9.0] days, P < 0.01). The hospital stay of the CHMG significantly decreased compared with that of the WMG (6.0 [range: 3.0–11.0] days vs 9.0 [range: 6.0–13.0] days, P < 0.01). The group was independently associated with negative conversion time (P < 0.01). The Mild/Moderate type: Negative conversion time significantly decreased in the CHMG compared with the WMG (6.0 [range: 2.0–11.0] days vs 8.0 [range: 3.0–12.0] days, P < 0.01). The hospital stay of the CHMG significantly decreased compared with that of the WMG (9.0 [range: 5.0–14.0] days vs 11.0 [range: 7.0–16.0] days, P < 0.01).

Conclusion

We found that the use of the JingYinGuBiao formula in Asymptomatic type patients and the JingYinQinHua formula in Mild/Moderate type patients is one of the most effective ways of treating SARS-CoV-2 Omicron infection because it could shorten negative conversion time and hospital stay.
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Journal of Herbal Medicine
Journal of Herbal Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
3.90
自引率
0.00%
发文量
94
期刊介绍: The Journal of Herbal Medicine, the official journal of the National Institute of Medical Herbalists, is a peer reviewed journal which aims to serve its readers as an authoritative resource on the profession and practice of herbal medicine. The content areas of the journal reflect the interests of Medical Herbalists and other health professionals interested in the clinical and professional application of botanical medicines. The objective is to strengthen the research and educational base of herbal medicine with research papers in the form of case studies, original research articles and reviews, monographs, clinical trials and relevant in vitro studies. It also publishes policy statements, opinion pieces, book reviews, conference proceedings and profession related information such as pharmacovigilance reports providing an information source for not only the Herbal Practitioner but any Health professional with an interest in phytotherapy.
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