Multitracer PET/CT Findings in a Case of Behavioral Variant Frontotemporal Dementia With Parkinsonism.

IF 9.6 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Clinical Nuclear Medicine Pub Date : 2025-02-01 Epub Date: 2024-12-02 DOI:10.1097/RLU.0000000000005611
Shuai Chen, Chang Fu, Jing-Yu Shao, Jun-Ling Xu, Jie-Wen Zhang
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Abstract

Abstracts: We report the clinical and multimodal PET/CT manifestations in a patient with behavioral variant frontotemporal dementia and parkinsonism. The 18 F-FDG PET scan revealed hypometabolism in the left supratentorial cortex. The 18 F-fluorodopa PET scan demonstrated decreased uptake in the bilateral striatum, most prominent in the head of caudate nucleus. The 18 F-florbetapir PET scan indicated an absence of β-amyloid deposition, whereas the 18 F-flortaucipir PET scan showed uptake in the left hemisphere neocortex. The clinical presentation and asymmetric neuroimaging features supported the underlying frontotemporal lobar degeneration-tau pathology.

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行为变异性额颞叶痴呆伴帕金森病的多示踪PET/CT表现。
摘要:我们报告一例行为变异性额颞叶痴呆和帕金森病患者的临床和多模态PET/CT表现。18F-FDG PET扫描显示左侧幕上皮层代谢低下。18f -氟多巴PET扫描显示双侧纹状体摄取减少,最突出的是尾状核头部。18F-flortaucipir PET扫描显示β-淀粉样蛋白沉积缺失,而18F-flortaucipir PET扫描显示左半球新皮层摄取。临床表现和不对称的神经影像学特征支持潜在的额颞叶变性-tau病理。
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来源期刊
Clinical Nuclear Medicine
Clinical Nuclear Medicine 医学-核医学
CiteScore
2.90
自引率
31.10%
发文量
1113
审稿时长
2 months
期刊介绍: Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.
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