Superscan in First Posttherapeutic 177 Lu-PSMA Scan.

IF 9.6 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Clinical Nuclear Medicine Pub Date : 2025-04-01 Epub Date: 2024-12-03 DOI:10.1097/RLU.0000000000005624
Merve Nida Calderon Tobar, Farise Yilmaz, Lütfü Perktaş
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Abstract

Abstract: This case highlights the effectiveness of 177 Lu-PSMA therapy in a 70-year-old man with castration-resistant prostate cancer who has extensive skeletal metastases in posttherapeutic whole-body imaging. A 70-year-old man with extensive skeletal metastases underwent 4 cycles of 177 Lu-PSMA-617 therapy. A whole-body 177 Lu-PSMA scan after the first cycle showed diffuse skeletal lesions, with minimal PSMA uptake in the kidneys and salivary glands. A whole-body scan after the fourth cycle of 177 Lu-PSMA showed a complete response of skeletal metastases with normal PSMA uptake in the kidneys and salivary glands. According to RECİP 1.0, the patient was considered a complete response.

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第一次治疗后177Lu-PSMA扫描的超扫描。
摘要:本病例强调了177Lu-PSMA治疗在70岁男性去势抵抗性前列腺癌患者治疗后全身成像中广泛骨骼转移的有效性。一例70岁男性广泛骨骼转移患者接受了4个周期的177 Lu-PSMA-617治疗。第一个周期后的全身177Lu-PSMA扫描显示弥漫性骨骼病变,肾脏和唾液腺中PSMA摄取极少。第四个周期177Lu-PSMA后的全身扫描显示骨骼转移完全缓解,肾脏和唾液腺的PSMA摄取正常。根据RECİP 1.0,认为患者完全缓解。
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来源期刊
Clinical Nuclear Medicine
Clinical Nuclear Medicine 医学-核医学
CiteScore
2.90
自引率
31.10%
发文量
1113
审稿时长
2 months
期刊介绍: Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.
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