Long-term clinical and angiographic outcome of T-and protrusion technique with ultrathin strut drug eluting stents.

IF 1.6 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Future cardiology Pub Date : 2024-12-01 Epub Date: 2024-12-04 DOI:10.1080/14796678.2024.2435205

Csaba A Dézsi, Judit Andréka, Amer M Sayour, Mónika Deák, Veronika Szentes, Zoltán Sebők, Zsolt Fi, Alexandru Achim, Zoltán Ruzsa

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Abstract

Objectives: Data about coronary bifurcations treated with ultrathin strut drug-eluting stents (DES) using T-and-protrusion (TAP) technique is limited.

Methods: In this study, a total of 84 consecutive patients, who underwent bifurcation percutaneous coronary intervention (PCI) with TAP technique using Orsiro® DES (Biotronik, Berlin, Germany), were included. All pre- and post-procedural data, as well as 1- and 2-year follow-up angiograms, were analyzed. Primary endpoints were procedural success and target lesion failure (TLF); secondary endpoints were all-cause mortality and major adverse cardiac and cerebrovascular events (MACCE) during follow-up.

Results: Procedural success was achieved in 100% of cases. TLF rate was higher in patients presented with acute coronary syndrome compared to the ones with chronic coronary syndrome (19% vs. 5% p = 0.09). All-cause mortality was 30% during follow-up, from which 26% was due to non-cardiovascular cause, and the MACCE rate was 46%.

Conclusions: Coronary bifurcations treated with ultrathin strut DES showed good short-term results and were associated with acceptable cardiovascular mortality. However, in these long-term patients, the rate of MACCE and non-cardiovascular death were rather high.

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t -突出技术与超薄支撑物药物洗脱支架的长期临床和血管造影结果。

目的：超薄支架药物洗脱支架（DES）治疗冠状动脉分叉的数据有限。方法：在本研究中，共纳入84例连续使用Orsiro®DES （Biotronik, Berlin, Germany）采用TAP技术行分岔经皮冠状动脉介入治疗（PCI）的患者。分析所有术前和术后数据，以及1年和2年随访血管造影。主要终点是手术成功和靶病变失败（TLF）；次要终点是随访期间的全因死亡率和主要心脑血管不良事件（MACCE）。结果：手术成功率100%。急性冠脉综合征患者的TLF率高于慢性冠脉综合征患者（19% vs. 5% p = 0.09）。随访期间全因死亡率为30%，其中26%为非心血管原因，MACCE率为46%。结论：超薄支架DES治疗冠状动脉分叉具有良好的短期效果，并与可接受的心血管死亡率相关。然而，在这些长期患者中，MACCE和非心血管死亡率相当高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Future cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.80

自引率

5.90%

发文量

期刊介绍： Research advances have contributed to improved outcomes across all specialties, but the rate of advancement in cardiology has been exceptional. Concurrently, the population of patients with cardiac conditions continues to grow and greater public awareness has increased patients" expectations of new drugs and devices. Future Cardiology (ISSN 1479-6678) reflects this new era of cardiology and highlights the new molecular approach to advancing cardiovascular therapy. Coverage will also reflect the major technological advances in bioengineering in cardiology in terms of advanced and robust devices, miniaturization, imaging, system modeling and information management issues.