Haozu Zhen, Yang Wang, Fei Zheng, Bo Yang, Xuemei Sun, Xueping Yang
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引用次数: 0
Abstract
Purpose: Insomnia is a global health issue that imposes social and economic burdens. Aromatherapy is regarded as a promising alternative medicine for improving sleep quality. This meta-analysis was conducted to explore the potential of aromatherapy for addressing insomnia.
Methods: Seven databases were searched for relevant randomized controlled trials (RCTs) from their inception through August 12, 2023. Data were synthesized using random-effect pairwise meta-analysis, with standardized mean difference (SMD) and 95% confidence interval (CI) reported. The risk of bias of each RCT was appraised using the Cochrane risk of bias tool. Subgroup and sensitivity analysis, publication bias diagnosis were also performed.
Results: A total of 14 studies with 1043 participants were included. The meta-analysis revealed a significant difference between the intervention and control groups (SMD: -1.63, 95% CI: -2.20 to -1.04). Sensitivity analysis showed that, whichever study was omitted, the conclusions of the remaining studies did not reverse. Among the 14 RCTs included, 6 were deemed to have a low overall risk of bias, and 8 were found to have some concerns. Subgroup analysis revealed that Iran had a more significant therapeutic effect than other regions. The effects of rose and citrus aurantium are more obvious than those of lavender. The different treatments in the control groups, intervention durations and sleep quality questionnaires had impacts on therapeutic effects, while discrepancies were not significant for different health conditions.
Conclusion: Aromatic essential oil has a significant therapeutic effect on insomnia. Further research on the mechanisms and guidelines for implementing aromatherapy is needed. This meta-analysis has been registered in PROSPERO with the ID CRD42023454070.
期刊介绍：
The journal Sleep and Breathing aims to reflect the state of the art in the international science and practice of sleep medicine. The journal is based on the recognition that management of sleep disorders requires a multi-disciplinary approach and diverse perspectives. The initial focus of Sleep and Breathing is on timely and original studies that collect, intervene, or otherwise inform all clinicians and scientists in medicine, dentistry and oral surgery, otolaryngology, and epidemiology on the management of the upper airway during sleep.
Furthermore, Sleep and Breathing endeavors to bring readers cutting edge information about all evolving aspects of common sleep disorders or disruptions, such as insomnia and shift work. The journal includes not only patient studies, but also studies that emphasize the principles of physiology and pathophysiology or illustrate potentially novel approaches to diagnosis and treatment. In addition, the journal features articles that describe patient-oriented and cost-benefit health outcomes research. Thus, with peer review by an international Editorial Board and prompt English-language publication, Sleep and Breathing provides rapid dissemination of clinical and clinically related scientific information. But it also does more: it is dedicated to making the most important developments in sleep disordered breathing easily accessible to clinicians who are treating sleep apnea by presenting well-chosen, well-written, and highly organized information that is useful for patient care.
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