Clinical and microbiological effectiveness of pulsed-xenon ultraviolet light disinfection in a neonatal intensive care unit in Japan

IF 3.9 3区医学 Q1 INFECTIOUS DISEASES Journal of Hospital Infection Pub Date : 2025-02-01 DOI:10.1016/j.jhin.2024.11.015

S. Komamizu , Y. Yamamoto , K. Morikane , Y. Kuwabara , M. Kondo , K. Tatebayashi , T. Koyama , D. Terazawa

{"title":"Clinical and microbiological effectiveness of pulsed-xenon ultraviolet light disinfection in a neonatal intensive care unit in Japan","authors":"S. Komamizu , Y. Yamamoto , K. Morikane , Y. Kuwabara , M. Kondo , K. Tatebayashi , T. Koyama , D. Terazawa","doi":"10.1016/j.jhin.2024.11.015","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Meticillin-resistant <em>Staphylococcus aureus</em> (MRSA) is a common causative agent of serious healthcare-related infections in neonatal intensive care units (NICUs). In adult ICUs, pulsed-xenon ultraviolet (PX-UV) disinfection of environmental surfaces, along with alcohol-based hand hygiene and terminal cleaning, has been demonstrated to reduce the MRSA acquisition rate.</div></div><div><h3>Aim</h3><div>To explore the impact of PX-UV use in NICUs on reducing MRSA transmission.</div></div><div><h3>Methods</h3><div>The incidence of newly detected MRSA cases was recorded for all patients between January 2021 and December 2022. UV irradiation was used in addition to terminal manual cleaning. During the baseline period, irradiation was performed on areas following the use by patients with MRSA; in the intervention period, irradiation was performed after each patient's use.</div></div><div><h3>Findings</h3><div>Though there was no observed change in the frequency of hand hygiene compliance throughout the study period, the total number of MRSA cases detected per 1000 patient-days decreased significantly.</div></div><div><h3>Conclusion</h3><div>In NICUs, UV irradiation of environmental surfaces, in addition to hand hygiene practices and conventional environmental maintenance, may be effective in reducing MRSA infection.</div></div>","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":"156 ","pages":"Pages 13-16"},"PeriodicalIF":3.9000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Hospital Infection","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0195670124003967","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Meticillin-resistant Staphylococcus aureus (MRSA) is a common causative agent of serious healthcare-related infections in neonatal intensive care units (NICUs). In adult ICUs, pulsed-xenon ultraviolet (PX-UV) disinfection of environmental surfaces, along with alcohol-based hand hygiene and terminal cleaning, has been demonstrated to reduce the MRSA acquisition rate.

Aim

To explore the impact of PX-UV use in NICUs on reducing MRSA transmission.

Methods

The incidence of newly detected MRSA cases was recorded for all patients between January 2021 and December 2022. UV irradiation was used in addition to terminal manual cleaning. During the baseline period, irradiation was performed on areas following the use by patients with MRSA; in the intervention period, irradiation was performed after each patient's use.

Findings

Though there was no observed change in the frequency of hand hygiene compliance throughout the study period, the total number of MRSA cases detected per 1000 patient-days decreased significantly.

Conclusion

In NICUs, UV irradiation of environmental surfaces, in addition to hand hygiene practices and conventional environmental maintenance, may be effective in reducing MRSA infection.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

脉冲氙气紫外线消毒在日本新生儿重症监护病房的临床和微生物效果。

背景：耐甲氧西林金黄色葡萄球菌（MRSA）是新生儿重症监护病房（NICUs）严重卫生保健相关感染的常见病原体。在成人icu中，环境表面的脉冲氙气紫外线（PX-UV）消毒，以及基于酒精的手部卫生和终端清洁，已被证明可以降低MRSA的获得率。然而，在nicu中使用PX-UV对减少MRSA传播的影响仍未被探索。方法：记录所有患者在2021年1月至2022年12月期间新检出MRSA病例的发生率。除末端人工清洗外，还采用紫外线照射。在基线期，对MRSA患者使用后的区域进行照射，而在干预期，在每位患者使用后进行照射。结果：在整个研究期间，虽然没有观察到手部卫生依从性的频率发生变化，但每1000个患者日检测到的MRSA病例总数显着下降。结论：在新生儿重症监护病房中，环境表面的紫外线照射，加上手部卫生习惯和常规的环境维护，可能有效减少MRSA感染。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Journal of Hospital Infection 医学-传染病学

CiteScore

12.70

自引率

5.80%

发文量

271

审稿时长

19 days

期刊介绍： The Journal of Hospital Infection is the editorially independent scientific publication of the Healthcare Infection Society. The aim of the Journal is to publish high quality research and information relating to infection prevention and control that is relevant to an international audience. The Journal welcomes submissions that relate to all aspects of infection prevention and control in healthcare settings. This includes submissions that: provide new insight into the epidemiology, surveillance, or prevention and control of healthcare-associated infections and antimicrobial resistance in healthcare settings; provide new insight into cleaning, disinfection and decontamination; provide new insight into the design of healthcare premises; describe novel aspects of outbreaks of infection; throw light on techniques for effective antimicrobial stewardship; describe novel techniques (laboratory-based or point of care) for the detection of infection or antimicrobial resistance in the healthcare setting, particularly if these can be used to facilitate infection prevention and control; improve understanding of the motivations of safe healthcare behaviour, or describe techniques for achieving behavioural and cultural change; improve understanding of the use of IT systems in infection surveillance and prevention and control.