Effects of Dialectical Behavior Therapy on Cognitive and Executive Functions in Men With Substance Use Disorder Under Methadone Maintenance Treatment: A Randomized Clinical Trial.

Kiamars Khezrian, Zahra Zanjani, Morad Rasouli Azad
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Abstract

Abstract: Substance use disorder is a major public health problem, and its treatment is one of the most challenging issues facing clinical professionals. This clinical trial study investigated the effects of the dialectical behavior therapy (DBT) on cognitive and executive functions in patients under methadone maintenance treatment (MMT). Participants included 50 people under MMT who referred to addiction treatment clinics in Kashan in 2018. They were randomly assigned to intervention (DBT + MMT) and control (MMT) groups. Participants in the intervention group received twelve 90-minute sessions of the DBT skills. The used assessments included Structured Clinical Interview for DSM-5 Axis I Disorders, Iowa Gambling Task, Wisconsin Card Sorting Task, and Tower of London Task. The results showed that DBT improved cognitive and executive function. Risky decision making (F = 4.1, p = 0.04), attention (F = 18.2, p = 0.001), cognitive flexibility (F = 18.5, p = 0.001), problem-solving (F = 18.5, p = 0.001), and planning (F = 14.10, p = 0.003) showed improvement in the intervention group following DBT. Therefore, it can be said that DBT alongside the MMT can be useful for patients under MMT.

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辩证行为疗法对美沙酮维持治疗下男性物质使用障碍患者认知和执行功能的影响:一项随机临床试验。
摘要:物质使用障碍是一个重大的公共卫生问题,其治疗是临床专业人员面临的最具挑战性的问题之一。本临床研究探讨辩证行为疗法(DBT)对美沙酮维持治疗(MMT)患者认知和执行功能的影响。参与者包括50名MMT下的人,他们在2018年转诊到卡尚的成瘾治疗诊所。他们被随机分为干预组(DBT + MMT)和对照组(MMT)。干预组的参与者接受了12次90分钟的DBT技能训练。使用的评估包括DSM-5 I轴障碍的结构化临床访谈,爱荷华州赌博任务,威斯康星州卡片分类任务和伦敦塔任务。结果表明,DBT改善了认知和执行功能。干预组风险决策(F = 4.1, p = 0.04)、注意力(F = 18.2, p = 0.001)、认知灵活性(F = 18.5, p = 0.001)、问题解决(F = 18.5, p = 0.001)和计划(F = 14.10, p = 0.003)在DBT后均有改善。因此,可以说在MMT的同时进行DBT对MMT下的患者是有用的。
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A New Holistic Theoretical Framework to Inform Opioid Use Disorder Management. Frequency and Intensity of Depressive Symptoms and Frequency of Prescribed Opioid Use Among Older Adults in the United States: Results of a National Survey. Predictors of Patient-Initiated Discharge From an Inpatient Withdrawal Management Service: A Sex-Based Study. Effects of Dialectical Behavior Therapy on Cognitive and Executive Functions in Men With Substance Use Disorder Under Methadone Maintenance Treatment: A Randomized Clinical Trial. Scenario Validation for Opioid Use Disorder Stigma-Related Nursing Simulations.
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