A Case Series of Patients Undergoing Bronchial Thermoplasty a Second Time for Severe Asthma.

IF 3.7 3区 医学 Q2 ALLERGY Journal of Asthma and Allergy Pub Date : 2024-11-30 eCollection Date: 2024-01-01 DOI:10.2147/JAA.S492730
Chuan T Foo, David Langton, Francis Thien
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Abstract

Bronchial thermoplasty is a treatment option for patients with severe asthma. We report a case series of 6 patients who underwent bronchial thermoplasty on two separate occasions for poorly controlled asthma. The repeat procedures were well tolerated with no unexpected complications. One patient developed a focal area of mild bronchiectasis on imaging 6-months after repeat treatment, but this was not felt to be clinically relevant. Individual responses to repeat bronchial thermoplasty were varied, with some patients showing great improvement after treatment, whereas others did not. This series highlights the safety and feasibility of performing repeat ablation on previously ablated airways, as well as the potential clinical benefit in a select group of patients.

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第二次支气管热成形术治疗严重哮喘的病例分析。
支气管热成形术是严重哮喘患者的一种治疗选择。我们报告了6例患者的病例系列,他们分别在两个不同的场合接受支气管热成形术治疗控制不良的哮喘。重复手术耐受性良好,无意外并发症。1例患者重复治疗6个月后影像学显示病灶轻度支气管扩张,但不认为与临床相关。重复支气管热成形术的个体反应各不相同,一些患者在治疗后表现出很大的改善,而另一些患者则没有。这一系列强调了对先前消融的气道进行重复消融的安全性和可行性,以及在选定的患者组中潜在的临床益处。
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来源期刊
Journal of Asthma and Allergy
Journal of Asthma and Allergy Medicine-Immunology and Allergy
CiteScore
5.30
自引率
6.20%
发文量
185
审稿时长
16 weeks
期刊介绍: An international, peer-reviewed journal publishing original research, reports, editorials and commentaries on the following topics: Asthma; Pulmonary physiology; Asthma related clinical health; Clinical immunology and the immunological basis of disease; Pharmacological interventions and new therapies. Although the main focus of the journal will be to publish research and clinical results in humans, preclinical, animal and in vitro studies will be published where they shed light on disease processes and potential new therapies.
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