Comparison of Immediate Outcomes of Pulmonary Valve-Sparing and Transannular Patch Techniques for Correction of Tetralogy of Fallot.

Q3 Medicine Sultan Qaboos University Medical Journal Pub Date : 2024-11-01 Epub Date: 2024-11-27 DOI:10.18295/squmj.11.2024.077
Mohammed H Al Ghafri, Sumaiyah O Al Toubi, Madan M Maddali, Panchatcharam M Sathiya, Sachin Jose, Hamood N Al-Kindi
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Abstract

Objectives: This study primarily aimed to compare the mechanical ventilation durations between pulmonary valve-sparing and transannular patch repair techniques in the surgical correction of Tetralogy of Fallot. Secondary objectives included comparison of demographic characteristics, cardiopulmonary bypass parameters, postoperative vasoactive inotrope requirements, incidence of cardiac conduction abnormalities, echocardiographic findings, intensive care unit and hospitalisation durations, reoperations rates, morbidity and mortality between the 2 approaches.

Methods: This retrospective cohort study was conducted at the Royal Hospital, Muscat, Oman, between January 2016 and December 2019. This study included 102 paediatric patients who underwent complete surgical correction of Tetralogy of Fallot over 3 years, either by a pulmonary valve-sparing technique (Group 1, n = 43) or by transannular patch repair (Group 2, n = 59). Data for both primary and secondary outcomes were extracted from hospital records.

Results: Mechanical ventilation duration was significantly shorter in Group 1 (P = 0.039). Patients in Group 1 were generally older, with shorter cardiopulmonary bypass and aortic clamp times, lower inotrope scores, and shorter chest tube retention, intensive care unit and hospitalisation periods. Junctional ectopic tachycardia and severe pulmonary regurgitation were significantly more common in Group 2, while right ventricular outflow tract peak pressure gradients were higher in Group 1. Multivariate analysis identified patient weight as the only independent predictor of mechanical ventilation duration.

Conclusion: Pulmonary valve preservation was associated with better early outcomes, including reduced mechanical ventilation duration, lower vasoactive inotrope scores, decreased postoperative arrhythmias and shorter hospital stay.

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保留肺瓣与经环贴片技术治疗法洛四联症的即时疗效比较。
目的:本研究的主要目的是比较在法洛四联症的手术矫正中,肺瓣保留和经环补片修复技术之间的机械通气时间。次要目的包括比较两种方法的人口学特征、体外循环参数、术后血管活性肌力要求、心传导异常发生率、超声心动图表现、重症监护病房和住院时间、再手术率、发病率和死亡率。方法:该回顾性队列研究于2016年1月至2019年12月在阿曼马斯喀特皇家医院进行。本研究纳入了102例法洛四联症患儿,他们在3年内接受了完全的手术矫正,通过肺瓣保留技术(组1,n = 43)或经环补片修复(组2,n = 59)。主要和次要结局的数据均取自医院记录。结果:1组患者机械通气时间明显缩短(P = 0.039)。第1组患者一般年龄较大,体外循环和主动脉夹夹次数较短,肌力评分较低,胸管保留时间较短,重症监护病房和住院时间较短。结界异位心动过速和严重肺返流在组2中更为常见,而右心室流出道峰值压力梯度在组1中更高。多变量分析确定患者体重是机械通气时间的唯一独立预测因子。结论:保留肺动脉瓣与较好的早期预后相关,包括减少机械通气时间、降低血管活性肌力评分、减少术后心律失常和缩短住院时间。
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来源期刊
CiteScore
2.00
自引率
0.00%
发文量
86
审稿时长
7 weeks
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