Entering the spatial age of parasite genomics.

IF 7 1区 医学 Q1 PARASITOLOGY Trends in parasitology Pub Date : 2025-01-01 Epub Date: 2024-12-05 DOI:10.1016/j.pt.2024.11.010
Sarah K Buddenborg, Stephen R Doyle
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Abstract

Reconciling organism-scale biology at cellular-scale resolution has been a monumental challenge. Recently, Gramberg et al. uncovered the spatial organisation of gene expression in the common liver fluke, Fasciola hepatica. These data provide new insights and opportunities for understanding the fundamental developmental and functional biology of parasites and new targets for control.

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进入寄生虫基因组学的空间时代。
在细胞尺度的分辨率下协调有机体尺度的生物学是一个巨大的挑战。最近,Gramberg等人发现了常见肝吸虫肝片吸虫基因表达的空间组织。这些数据为了解寄生虫的基本发育和功能生物学以及新的控制靶点提供了新的见解和机会。
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来源期刊
Trends in parasitology
Trends in parasitology 医学-寄生虫学
CiteScore
14.00
自引率
3.10%
发文量
148
审稿时长
6-12 weeks
期刊介绍: Since its inception as Parasitology Today in 1985, Trends in Parasitology has evolved into a highly esteemed review journal of global significance, reflecting the importance of medical and veterinary parasites worldwide. The journal serves as a hub for communication among researchers across all disciplines of parasitology, encompassing endoparasites, ectoparasites, transmission vectors, and susceptible hosts. Each monthly issue of Trends in Parasitology offers authoritative, cutting-edge, and yet accessible review articles, providing a balanced and comprehensive overview, along with opinion pieces offering personal and novel perspectives. Additionally, the journal publishes a variety of short articles designed to inform and stimulate thoughts in a lively and widely-accessible manner. These include Science & Society (discussing the interface between parasitology and the general public), Spotlight (highlighting recently published research articles), Forum (presenting single-point hypotheses), Parasite/Vector of the Month (featuring a modular display of the selected species), Letter (providing responses to recent articles in Trends in Parasitology), and Trendstalk (conducting interviews). Please note that the journal exclusively publishes literature reviews based on published data, with systematic reviews, meta-analysis, and unpublished primary research falling outside our scope.
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