Examining the implementation of a multi-site evidence-based intervention to reduce fluoroquinolone usage: A qualitative content analysis of staff interviews to identify facilitators and barriers.

IF 3.1 2区 工程技术 Q2 ENGINEERING, INDUSTRIAL Applied Ergonomics Pub Date : 2024-12-04 DOI:10.1016/j.apergo.2024.104419
Demetrius Solomon, Jukrin Moon, Vishala Parmasad, Sara Hernandez, Douglas Wiegmann, Nasia Safdar
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Abstract

Clostridioides difficile infection is the most common healthcare-associated infection, causing almost half a million infections in the United States annually. Inappropriate antibiotic usage is a known risk factor. Antibiotic stewardship efforts aim to optimize prescribing. Evidence supports pre-prescription authorization as a highly effective intervention. A pre-prescription intervention for fluoroquinolone antibiotics via a computerized clinical decision support tool called a "best practice alert" (BPA) embedded in the patient's electronic health records has high potential for improving antibiotic stewardship. However, information is scant about the factors that might impact the uptake and effectiveness of this BPA and other similar evidence-based interventions when spread and adopted across multiple independent sites. Therefore, we utilized the Consolidated Framework for Implementation Research (CFIR) to understand the facilitators and barriers to the implementation process that influence clinical and implementation outcomes. In doing so, we conducted semi-structured interviews with 18 healthcare professionals across four hospitals. Our research team performed a qualitative analysis to understand the contextual factors influencing the implementation outcomes, such as acceptability and sustainability.

Takeaways: The following themes highlight the factors affecting the implementation of this healthcare innovation.

Intervention characteristics domain: Designing interventions that are customizable and low maintenance.

Inner setting domain: Maturity level of the Antibiotic Stewardship Program.

Individuals domain: Implementer's experience/attitudes in implementing healthcare innovations.

Outer setting domain: The ability to prioritize initiatives as the organization responds to unintended circumstances (e.g., COVID).

Process domain: Adapting implementation approaches and strategies as technology spreads.

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审查减少氟喹诺酮类药物使用的多地点循证干预措施的实施情况:对工作人员访谈的定性内容分析,以确定促进因素和障碍。
艰难梭菌感染是最常见的医疗相关感染,每年在美国造成近50万例感染。抗生素使用不当是一个已知的危险因素。抗生素管理工作旨在优化处方。证据支持处方前授权是一种非常有效的干预措施。通过嵌入患者电子健康记录的计算机化临床决策支持工具(称为“最佳实践警报”(BPA))对氟喹诺酮类抗生素进行处方前干预,具有改善抗生素管理的巨大潜力。然而,关于在多个独立地点传播和采用双酚a和其他类似循证干预措施时可能影响其吸收和有效性的因素的信息很少。因此,我们利用实施研究综合框架(CFIR)来了解影响临床和实施结果的实施过程的促进因素和障碍。为此,我们对四家医院的18名医疗保健专业人员进行了半结构化访谈。我们的研究团队进行了定性分析,以了解影响实施结果的背景因素,如可接受性和可持续性。要点:以下主题突出了影响这一医疗保健创新实施的因素。干预特征领域:设计可定制和低维护的干预。内部设置领域:抗生素管理计划的成熟度水平。个人领域:实施医疗保健创新的实施者的经验/态度。外部设置域:在组织响应意外情况(例如,COVID)时确定计划优先级的能力。过程域:随着技术的传播,调整实现方法和策略。
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来源期刊
Applied Ergonomics
Applied Ergonomics 工程技术-工程:工业
CiteScore
7.50
自引率
9.40%
发文量
248
审稿时长
53 days
期刊介绍: Applied Ergonomics is aimed at ergonomists and all those interested in applying ergonomics/human factors in the design, planning and management of technical and social systems at work or leisure. Readership is truly international with subscribers in over 50 countries. Professionals for whom Applied Ergonomics is of interest include: ergonomists, designers, industrial engineers, health and safety specialists, systems engineers, design engineers, organizational psychologists, occupational health specialists and human-computer interaction specialists.
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