Efficacy of a couple-based intervention addressing sexual concerns for breast cancer survivors: Results of a randomized controlled trial.

IF 6.1 2区 医学 Q1 ONCOLOGY Cancer Pub Date : 2025-01-01 Epub Date: 2024-12-08 DOI:10.1002/cncr.35685
Jennifer Barsky Reese, Stephen J Lepore, Kristen A Sorice, Lauren A Zimmaro, Jill Hasler, Elizabeth Handorf, Mary B Daly, Alexandra K Zaleta, Kelly Westbrook, Laura S Porter
{"title":"Efficacy of a couple-based intervention addressing sexual concerns for breast cancer survivors: Results of a randomized controlled trial.","authors":"Jennifer Barsky Reese, Stephen J Lepore, Kristen A Sorice, Lauren A Zimmaro, Jill Hasler, Elizabeth Handorf, Mary B Daly, Alexandra K Zaleta, Kelly Westbrook, Laura S Porter","doi":"10.1002/cncr.35685","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Sexual concerns are common and problematic for breast cancer survivors. Partner and relationship factors often play a key role in determining survivors' sexual adjustment, making it likely that couple-based interventions that integrate survivors' partners could be especially promising for addressing survivors' sexual concerns. Yet few such interventions have been tested. The objective of this study was to evaluate the efficacy of the Intimacy Enhancement (IE) intervention, a four-session, couple-based intervention addressing breast cancer survivors' sexual concerns by telephone in a randomized controlled trial.</p><p><strong>Methods: </strong>Female posttreatment breast cancer survivors reporting sexual concerns and their intimate partners (N = 120 couples; 240 participants) were randomized either to the IE intervention or to Living Healthy Together (LHT), an active control intervention of equivalent length. Outcomes (measured at baseline, postintervention, and at 3 and 6 months postintervention) included breast cancer survivors' sexual function (primary), partners' sexual function (secondary), and survivors' and partners' psychosocial and relationship outcomes (secondary). Mixed linear regression models examined intervention effects on outcomes at all follow-ups.</p><p><strong>Results: </strong>Model-based estimates of intervention effects showed greater improvements in survivors' overall sexual function, sexual satisfaction, arousal, lubrication, and orgasm at postintervention (p < .05). Effects on survivors' 3-month and 6-month sexual functioning or other secondary outcomes were minimal. Most couples completed all IE sessions (97%) and LHT (92%), and satisfaction ratings were high.</p><p><strong>Conclusions: </strong>Compared with an active control intervention, the IE intervention had significant short-term benefits for survivors' sexual function. Efforts may be needed to increase the longevity of the positive effects, such as more frequent or adjunctive treatments.</p>","PeriodicalId":138,"journal":{"name":"Cancer","volume":" ","pages":"e35685"},"PeriodicalIF":6.1000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11696781/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/cncr.35685","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/8 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Sexual concerns are common and problematic for breast cancer survivors. Partner and relationship factors often play a key role in determining survivors' sexual adjustment, making it likely that couple-based interventions that integrate survivors' partners could be especially promising for addressing survivors' sexual concerns. Yet few such interventions have been tested. The objective of this study was to evaluate the efficacy of the Intimacy Enhancement (IE) intervention, a four-session, couple-based intervention addressing breast cancer survivors' sexual concerns by telephone in a randomized controlled trial.

Methods: Female posttreatment breast cancer survivors reporting sexual concerns and their intimate partners (N = 120 couples; 240 participants) were randomized either to the IE intervention or to Living Healthy Together (LHT), an active control intervention of equivalent length. Outcomes (measured at baseline, postintervention, and at 3 and 6 months postintervention) included breast cancer survivors' sexual function (primary), partners' sexual function (secondary), and survivors' and partners' psychosocial and relationship outcomes (secondary). Mixed linear regression models examined intervention effects on outcomes at all follow-ups.

Results: Model-based estimates of intervention effects showed greater improvements in survivors' overall sexual function, sexual satisfaction, arousal, lubrication, and orgasm at postintervention (p < .05). Effects on survivors' 3-month and 6-month sexual functioning or other secondary outcomes were minimal. Most couples completed all IE sessions (97%) and LHT (92%), and satisfaction ratings were high.

Conclusions: Compared with an active control intervention, the IE intervention had significant short-term benefits for survivors' sexual function. Efforts may be needed to increase the longevity of the positive effects, such as more frequent or adjunctive treatments.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
以夫妻为基础的干预对乳腺癌幸存者解决性问题的有效性:一项随机对照试验的结果。
背景:对乳腺癌幸存者来说,性方面的担忧很常见,也很成问题。伴侣和关系因素通常在决定幸存者的性调整方面起着关键作用,因此,结合幸存者伴侣的夫妻干预可能特别有希望解决幸存者的性问题。然而,此类干预措施很少经过测试。本研究的目的是在一项随机对照试验中评估亲密增强(IE)干预的效果,这是一项四期、以夫妻为基础的干预,通过电话解决乳腺癌幸存者的性问题。方法:报告性担忧的女性乳腺癌治疗后幸存者及其亲密伴侣(N = 120对夫妇;240名参与者)被随机分配到IE干预组或一起健康生活(LHT)组,这是一种相同长度的积极对照干预。结果(在基线、干预后、干预后3个月和6个月测量)包括乳腺癌幸存者的性功能(主要)、伴侣的性功能(次要)、幸存者和伴侣的社会心理和关系结果(次要)。混合线性回归模型检验了干预对所有随访结果的影响。结果:基于模型的干预效果估计显示,干预后幸存者的整体性功能、性满意度、性兴奋、润滑和性高潮有更大的改善(p)。结论:与主动对照干预相比,IE干预对幸存者的性功能有显著的短期益处。可能需要努力延长积极效果的持续时间,例如更频繁或辅助治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Cancer
Cancer 医学-肿瘤学
CiteScore
13.10
自引率
3.20%
发文量
480
审稿时长
2-3 weeks
期刊介绍: The CANCER site is a full-text, electronic implementation of CANCER, an Interdisciplinary International Journal of the American Cancer Society, and CANCER CYTOPATHOLOGY, a Journal of the American Cancer Society. CANCER publishes interdisciplinary oncologic information according to, but not limited to, the following disease sites and disciplines: blood/bone marrow; breast disease; endocrine disorders; epidemiology; gastrointestinal tract; genitourinary disease; gynecologic oncology; head and neck disease; hepatobiliary tract; integrated medicine; lung disease; medical oncology; neuro-oncology; pathology radiation oncology; translational research
期刊最新文献
Addressing socioeconomic barriers in the implementation of American Society of Clinical Oncology palliative care guidelines. Association of mental health treatment receipt with cancer screening among US adults with a history of anxiety or depression. Impact of smoking status on engagement in remote symptom monitoring after oncologic surgery: Implications for symptom management and readmission rates. The long road to unbiased estimates of pancreatic cancer incidence in the hereditary breast and ovarian cancer syndrome. A phase 2 basket study of talabostat, a small-molecule inhibitor of dipeptidyl peptidases, administered in combination with pembrolizumab in patients with advanced solid cancers.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1