{"title":"Biosensors for early stroke detection.","authors":"Firoozeh Alavian, Fatemeh Khodabakhshi, Fatemeh Heidary Chenary","doi":"10.1016/j.cca.2024.120079","DOIUrl":null,"url":null,"abstract":"<p><p>This article aims to provide a comprehensive review of the latest advances in biosensor technology for early stroke diagnosis. Analyzing current research from authoritative databases highlights the significance of biosensors in improving stroke detection and treatment outcomes, discusses their diagnostic capabilities, and addresses the challenges that must be overcome for broader clinical application. This review utilizes updated information and valid research from ISI, Google Scholar, Science Direct, Scopus, and PubMed to examine recent developments in biosensors applicable to early stroke diagnosis. The results indicate that biosensors are crucial for the early detection of strokes, and enhance treatment efficacy. The biosensors studied in this research serve as rapid and non-intrusive diagnostic instruments with exceptional precision and detection capabilities. Cutting-edge biosensors can identify distinct stroke-related biomarkers, offering rapid and non-invasive diagnostic solutions to improve stroke care outcomes. Despite these advancements, significant challenges remain regarding the sensitivity, specificity, and reliability of biosensors. These issues must be resolved to facilitate their widespread implementation in clinical settings.</p>","PeriodicalId":10205,"journal":{"name":"Clinica Chimica Acta","volume":" ","pages":"120079"},"PeriodicalIF":3.2000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinica Chimica Acta","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.cca.2024.120079","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/4 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
This article aims to provide a comprehensive review of the latest advances in biosensor technology for early stroke diagnosis. Analyzing current research from authoritative databases highlights the significance of biosensors in improving stroke detection and treatment outcomes, discusses their diagnostic capabilities, and addresses the challenges that must be overcome for broader clinical application. This review utilizes updated information and valid research from ISI, Google Scholar, Science Direct, Scopus, and PubMed to examine recent developments in biosensors applicable to early stroke diagnosis. The results indicate that biosensors are crucial for the early detection of strokes, and enhance treatment efficacy. The biosensors studied in this research serve as rapid and non-intrusive diagnostic instruments with exceptional precision and detection capabilities. Cutting-edge biosensors can identify distinct stroke-related biomarkers, offering rapid and non-invasive diagnostic solutions to improve stroke care outcomes. Despite these advancements, significant challenges remain regarding the sensitivity, specificity, and reliability of biosensors. These issues must be resolved to facilitate their widespread implementation in clinical settings.
期刊介绍：
The Official Journal of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)
Clinica Chimica Acta is a high-quality journal which publishes original Research Communications in the field of clinical chemistry and laboratory medicine, defined as the diagnostic application of chemistry, biochemistry, immunochemistry, biochemical aspects of hematology, toxicology, and molecular biology to the study of human disease in body fluids and cells.
The objective of the journal is to publish novel information leading to a better understanding of biological mechanisms of human diseases, their prevention, diagnosis, and patient management. Reports of an applied clinical character are also welcome. Papers concerned with normal metabolic processes or with constituents of normal cells or body fluids, such as reports of experimental or clinical studies in animals, are only considered when they are clearly and directly relevant to human disease. Evaluation of commercial products have a low priority for publication, unless they are novel or represent a technological breakthrough. Studies dealing with effects of drugs and natural products and studies dealing with the redox status in various diseases are not within the journal''s scope. Development and evaluation of novel analytical methodologies where applicable to diagnostic clinical chemistry and laboratory medicine, including point-of-care testing, and topics on laboratory management and informatics will also be considered. Studies focused on emerging diagnostic technologies and (big) data analysis procedures including digitalization, mobile Health, and artificial Intelligence applied to Laboratory Medicine are also of interest.
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