Increased expression of epithelial-mesenchymal transition markers associated with recurrence of sinonasal inverted papilloma

IF 7.2 2区 医学 Q1 OTORHINOLARYNGOLOGY International Forum of Allergy & Rhinology Pub Date : 2024-12-09 DOI:10.1002/alr.23501
Junhao Tu MD, PhD, Fan Jiang MD, Jing Liu PhD, Hsiao Hui Ong PhD, Zhiqun Huang MD, PhD, Keshuang Wang MD, PhD, Qing Luo MD, PhD, Li Shi MD, PhD, Jing Ye MD, PhD, Deyun Wang MD, PhD
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引用次数: 0

Abstract

Key points

  • Sinonasal inverted papilloma (SNIP) is a benign epithelial proliferative disease with a high recurrence rate.
  • The role of epithelial-mesenchymal transition (EMT) in the pathogenesis of SNIP remains unclear.
  • EMT marker expression is elevated in SNIP tissues and is associated with its recurrence.
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鼻腔内翻性乳头状瘤复发与上皮-间质转化标志物表达增加相关。
鼻窦内翻性乳头状瘤(SNIP)是一种复发率高的良性上皮增生性疾病。上皮间质转化(epithelial-mesenchymal transition, EMT)在SNIP发病机制中的作用尚不清楚。EMT标记物表达在SNIP组织中升高,并与其复发相关。
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来源期刊
CiteScore
11.70
自引率
10.90%
发文量
185
审稿时长
6-12 weeks
期刊介绍: International Forum of Allergy & Rhinologyis a peer-reviewed scientific journal, and the Official Journal of the American Rhinologic Society and the American Academy of Otolaryngic Allergy. International Forum of Allergy Rhinology provides a forum for clinical researchers, basic scientists, clinicians, and others to publish original research and explore controversies in the medical and surgical treatment of patients with otolaryngic allergy, rhinologic, and skull base conditions. The application of current research to the management of otolaryngic allergy, rhinologic, and skull base diseases and the need for further investigation will be highlighted.
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