Junhao Tu MD, PhD, Fan Jiang MD, Jing Liu PhD, Hsiao Hui Ong PhD, Zhiqun Huang MD, PhD, Keshuang Wang MD, PhD, Qing Luo MD, PhD, Li Shi MD, PhD, Jing Ye MD, PhD, Deyun Wang MD, PhD
{"title":"Increased expression of epithelial-mesenchymal transition markers associated with recurrence of sinonasal inverted papilloma","authors":"Junhao Tu MD, PhD, Fan Jiang MD, Jing Liu PhD, Hsiao Hui Ong PhD, Zhiqun Huang MD, PhD, Keshuang Wang MD, PhD, Qing Luo MD, PhD, Li Shi MD, PhD, Jing Ye MD, PhD, Deyun Wang MD, PhD","doi":"10.1002/alr.23501","DOIUrl":null,"url":null,"abstract":"<div>\n \n <section>\n \n <h3> Key points</h3>\n \n <div>\n <ul>\n \n <li>Sinonasal inverted papilloma (SNIP) is a benign epithelial proliferative disease with a high recurrence rate.</li>\n \n <li>The role of epithelial-mesenchymal transition (EMT) in the pathogenesis of SNIP remains unclear.</li>\n \n <li>EMT marker expression is elevated in SNIP tissues and is associated with its recurrence.</li>\n </ul>\n </div>\n </section>\n </div>","PeriodicalId":13716,"journal":{"name":"International Forum of Allergy & Rhinology","volume":"15 3","pages":"354-358"},"PeriodicalIF":7.2000,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Forum of Allergy & Rhinology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/alr.23501","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Key points
Sinonasal inverted papilloma (SNIP) is a benign epithelial proliferative disease with a high recurrence rate.
The role of epithelial-mesenchymal transition (EMT) in the pathogenesis of SNIP remains unclear.
EMT marker expression is elevated in SNIP tissues and is associated with its recurrence.
期刊介绍:
International Forum of Allergy & Rhinologyis a peer-reviewed scientific journal, and the Official Journal of the American Rhinologic Society and the American Academy of Otolaryngic Allergy.
International Forum of Allergy Rhinology provides a forum for clinical researchers, basic scientists, clinicians, and others to publish original research and explore controversies in the medical and surgical treatment of patients with otolaryngic allergy, rhinologic, and skull base conditions. The application of current research to the management of otolaryngic allergy, rhinologic, and skull base diseases and the need for further investigation will be highlighted.