Sarah E Park, Elaine Ma, Caitlyn Dagenet, Maria A Aleshin, Heather M Holahan, Vivian Y Shi, Jennifer L Hsiao
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引用次数: 0
Abstract
Introduction: Chronic urticaria (CU) is frequently a debilitating skin condition characterized by recurrent and spontaneous wheal and flares with significant impact on quality of life. This systematic review examines the impact of CU on sexual health.
Methods: A systematic review using PubMed, Embase, Web of Science, and Cochrane library databases was conducted for articles on sexual health in chronic urticaria.
Results: The database search produced 741 articles, of which 14 articles met inclusion criteria. Study design, patient demographics, disease characteristics, measures used to assess sexuality or sexual function, and study results were independently extracted for each article by two researchers. Any discrepancies were resolved to consensus by a third reviewer. Sexual dysfunction was common in patients with CU and its severity is associated with increased disease activity and poor disease control.
Conclusion: Sexual dysfunction is common in patients with CU, and it negatively affects their quality of life (QoL), body image, sleep quality, and mental health. Incorporating sexual health assessments into CU trials will allow for valuable insights into efficacy of study medications on this important QoL domain. Increased awareness of sexual impairment in CU is needed to provide comprehensive care.
慢性荨麻疹（CU）通常是一种衰弱的皮肤状况，其特征是反复发作和自发的皮疹和耀斑，对生活质量有重大影响。本系统综述探讨了CU对性健康的影响。方法：系统回顾PubMed、Embase、Web of Science和Cochrane图书馆数据库中关于慢性荨麻疹性健康的文章。结果：数据库检索到741篇文章，其中14篇符合纳入标准。研究设计、患者人口统计、疾病特征、用于评估性或性功能的措施以及研究结果由两名研究人员独立地为每篇文章提取。任何差异由第三位审稿人解决以达成一致意见。性功能障碍在CU患者中很常见，其严重程度与疾病活动性增加和疾病控制不良有关。结论：性功能障碍在CU患者中普遍存在，并对患者的生活质量、身体形象、睡眠质量和心理健康产生负面影响。将性健康评估纳入CU试验将允许对研究药物在这一重要的生活质量领域的功效有价值的见解。需要提高对CU中性障碍的认识，以提供全面的护理。
期刊介绍：
Dermatology and Therapy is an international, open access, peer-reviewed, rapid publication journal (peer review in 2 weeks, published 3–4 weeks from acceptance). The journal is dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of dermatological therapies. Studies relating to diagnosis, pharmacoeconomics, public health and epidemiology, quality of life, and patient care, management, and education are also encouraged.
Areas of focus include, but are not limited to all clinical aspects of dermatology, such as skin pharmacology; skin development and aging; prevention, diagnosis, and management of skin disorders and melanomas; research into dermal structures and pathology; and all areas of aesthetic dermatology, including skin maintenance, dermatological surgery, and lasers.
The journal is of interest to a broad audience of pharmaceutical and healthcare professionals and publishes original research, reviews, case reports/case series, trial protocols, and short communications. Dermatology and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an International and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of quality research, which may be considered of insufficient interest by other journals. The journal appeals to a global audience and receives submissions from all over the world.
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