[Retrograde cricopharyngeal dysfunction (inability to belch) - a »new« diagnosis that deserves attention].

Lakartidningen Pub Date : 2024-12-05
Anders Lehmann
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引用次数: 0

Abstract

The belching reflex involves transient lower oesophageal sphincter relaxation and relaxation of the cricopharyngeus (CP). In some individuals, the  latter stage fails,leading to return of gas to the stomach. This pattern is then repeated, which is accompanied by chest pain and loud, gurgling noises. Abdominal distension, epigastric pain and excessive flatulence are other common symptoms. Since CP relaxation is normal during deglutition, the syndrome is called retrograde CP dysfunction (RCPD). The anamnesis should be supported by e.g. manometry under conditions stimulating belching to validate the diagnosis. First-line treatment is injection of botulinum toxin (botox) into the CP. The prevalence is unknown and although RCPD is rare, a large number of confirmed and self-diagnosed RCPD patients have emerged in social media after dissemination of the efficacy of botox. RCPD patients suffer considerably, and awareness of the disease must therefore increase in the medical community.

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[逆行性环咽功能障碍(不能打嗝)——值得关注的“新”诊断]。
打嗝反射包括短暂性食管下括约肌松弛和环咽肌松弛。在一些人身上,后一阶段失败,导致气体返回胃。然后重复这种模式,伴随着胸痛和大声的咯咯声。腹胀、上腹痛和过度胀气是其他常见症状。由于在吞咽过程中CP放松是正常的,因此该综合征被称为逆行性CP功能障碍(RCPD)。在刺激打嗝的条件下,应该通过测压来支持记忆,以验证诊断。一线治疗方法是在CP内注射肉毒杆菌毒素(botox)。RCPD的患病率尚不清楚,虽然RCPD很少见,但在社交媒体上传播了肉毒杆菌的疗效后,出现了大量确诊和自诊断的RCPD患者。RCPD患者遭受了相当大的痛苦,因此医学界必须提高对这种疾病的认识。
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来源期刊
Lakartidningen
Lakartidningen Medicine-Medicine (all)
CiteScore
0.30
自引率
0.00%
发文量
134
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