[Cholangiocarcinomas].

Chirurgie (Heidelberg, Germany) Pub Date : 2025-01-01 Epub Date: 2024-12-10 DOI:10.1007/s00104-024-02200-z
Wenzel Schöning, Philipp K Haber, Johann Pratschke
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Abstract

The term cholangiocarcinoma (CCA) includes a group of malignant tumors that develop in the efferent bile ducts and are characterized by a high degree of heterogeneity. These differences between intrahepatic, perihilar and distal CCAs run through all aspects of the disease including the etiology, pathogenesis, symptoms, diagnostics and treatment. This review article presents the current developments in this field of diseases. We highlight surgical innovations in the clinical routine and the application of new systemic forms of treatment to augment the oncological radicality of surgery.

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[Cholangiocarcinomas]。
胆管癌(CCA)一词包括一组发生在出胆管的恶性肿瘤,其特点是高度异质性。肝内、门周和远端cca之间的这些差异贯穿于疾病的各个方面,包括病因、发病机制、症状、诊断和治疗。本文综述了这一疾病领域的最新进展。我们强调在临床常规手术创新和应用新的系统形式的治疗,以增加肿瘤手术的根治性。
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