Vaccine stock-outs: A preventable health facility obstacle contributing to missed vaccinations in South African children

IF 4.5 3区 医学 Q2 IMMUNOLOGY Vaccine Pub Date : 2025-01-25 DOI:10.1016/j.vaccine.2024.126583
Natasha M. Masemola , Rosemary J. Burnett , Portia C. Makamba-Mutevedzi , Marione Schönfeldt , Lesley J. Bamford , Zeenat Ismail , Shabir A. Madhi , Johanna C. Meyer
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Abstract

In 2019 the National Department of Health (NDoH) conducted a national immunisation coverage survey of caregivers of children aged 24–35 months in all 52 districts of South Africa, and reported a national fully immunised under one year-old coverage of 83.9 %, and 76.8 % coverage for all vaccines scheduled up to 18 months of age. This retrospective, descriptive study was a secondary data analysis of 3576 validated Microsoft Excel® records containing the reasons for missed vaccinations collected by field workers during the 2019 national survey. The reason “vaccine out of stock” had been captured by field workers from children's vaccination cards, while other reasons given by caregivers had been captured either as pre-defined codes or free text. Free text reasons were analysed and additional codes created, and all reasons were categorised. In total, 3576 caregivers gave 8116 reasons for 8056 doses that had been missed by their children. Reasons related to health facility obstacles (HFOs) (67.9 %; 2429/3576) and personal obstacles (34.6 %; 1237/3576) constituted the major categories of reasons for missed vaccinations. Of all vaccines missed because of HFO-related reasons, 57.8 % (1403/2429) were missed because of vaccine stock-outs, affecting 39.2 % (1403/3576) of children. Other important HFOs included lack of access to vaccination services (24.5 %; 595/2429); and information about missed vaccinations and the need to return for catch-up not being shared with caregivers (17.1 %; 416/2429). These results were stratified by district and shared with the NDoH, who have initiated several projects in collaboration with other stakeholders, focusing mainly on building capacity for effective vaccine management to prevent vaccine stock-outs, and ensuring that all children are able to access vaccination services. The results of this study can be used as a baseline against which the success of future interventions emanating from these projects can be measured.
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疫苗缺货:可预防的卫生设施障碍导致南非儿童错过疫苗接种。
2019年,国家卫生部(NDoH)对南非所有52个区24-35个月儿童的照顾者进行了全国免疫覆盖率调查,报告称,全国1岁以下儿童的完全免疫覆盖率为83.9%,18个月以下所有疫苗的覆盖率为76.8%。这项回顾性描述性研究是对2019年全国调查期间现场工作人员收集的3576条经过验证的Microsoft Excel®记录的二次数据分析,这些记录包含错过接种疫苗的原因。外勤工作人员从儿童疫苗接种卡中记录了“疫苗缺货”的原因,而护理人员提供的其他原因则以预定义代码或自由文本的形式记录下来。分析了自由文本原因,创建了附加代码,并对所有原因进行了分类。总共有3576名护理人员为他们的孩子错过的8056剂疫苗给出了8116个理由。与卫生设施障碍有关的原因(67.9%;2429/3576)和个人障碍(34.6%;1237/3576)构成错过接种疫苗的主要原因类别。在所有因hfo相关原因错过的疫苗中,57.8%(1403/2429)因疫苗缺货而错过,影响39.2%(1403/3576)的儿童。其他重要的hfo包括无法获得疫苗接种服务(24.5%;595/2429);未接种疫苗和需要返回补种的信息未与护理人员共享(17.1%;416/2429)。这些结果按地区分层,并与国家卫生部分享。国家卫生部与其他利益攸关方合作启动了几个项目,主要侧重于建设有效疫苗管理的能力,以防止疫苗缺货,并确保所有儿童都能获得疫苗接种服务。这项研究的结果可以作为衡量这些项目产生的未来干预措施成功与否的基准。
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来源期刊
Vaccine
Vaccine 医学-免疫学
CiteScore
8.70
自引率
5.50%
发文量
992
审稿时长
131 days
期刊介绍: Vaccine is unique in publishing the highest quality science across all disciplines relevant to the field of vaccinology - all original article submissions across basic and clinical research, vaccine manufacturing, history, public policy, behavioral science and ethics, social sciences, safety, and many other related areas are welcomed. The submission categories as given in the Guide for Authors indicate where we receive the most papers. Papers outside these major areas are also welcome and authors are encouraged to contact us with specific questions.
期刊最新文献
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