High-Efficiency, Prevascularization-Free Macroencapsulation System for Subcutaneous Transplantation of Pancreatic Islets for Enhanced Diabetes Treatment (Adv. Mater. 50/2024)

IF 26.8 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Advanced Materials Pub Date : 2024-12-12 DOI:10.1002/adma.202470401
Seunggyu Jeon, Jun-Ho Heo, Noehyun Myung, Ji Yeong Shin, Min Kyeong Kim, Hyun-Wook Kang
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Abstract

Islet Macroencapsulation System for Subcutaneous Transplantation

A novel multilayered macroencapsulation system positions islets within specialized micro-shell layers to maximize their proximity to surrounding host vasculature in subcutaneous tissue. This innovative design improves the supply of nutrients/oxygen, while the optimized islet density facilitates efficient functionality in low-vascular environments, offering a promising solution for enhancing the treatment of type I diabetes. More details can be found in article number 2408329 by Hyun-Wook Kang and co-workers.

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用于胰岛皮下移植强化糖尿病治疗的高效、无预血管大胶囊系统(Adv. Mater. 50/2024)
用于皮下移植的胰岛大胶囊系统
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来源期刊
Advanced Materials
Advanced Materials 工程技术-材料科学:综合
CiteScore
43.00
自引率
4.10%
发文量
2182
审稿时长
2 months
期刊介绍: Advanced Materials, one of the world's most prestigious journals and the foundation of the Advanced portfolio, is the home of choice for best-in-class materials science for more than 30 years. Following this fast-growing and interdisciplinary field, we are considering and publishing the most important discoveries on any and all materials from materials scientists, chemists, physicists, engineers as well as health and life scientists and bringing you the latest results and trends in modern materials-related research every week.
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