Single Atom Engineered Antibiotics Overcome Bacterial Resistance (Adv. Mater. 50/2024)

IF 26.8 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Advanced Materials Pub Date : 2024-12-12 DOI:10.1002/adma.202470402

David Panáček, Jan Belza, Lucie Hochvaldová, Zdeněk Baďura, Giorgio Zoppellaro, Martin Šrejber, Tomáš Malina, Veronika Šedajová, Markéta Paloncýová, Rostislav Langer, Lukáš Zdražil, Jianrong Zeng, Lina Li, En Zhao, Zupeng Chen, Zhiqiang Xiong, Ruibin Li, Aleš Panáček, Renata Večeřová, Pavla Kučová, Milan Kolář, Michal Otyepka, Aristides Bakandritsos, Radek Zbořil

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Abstract

Multi-Drug Resistance

Single atoms of manganese, tightly bonded to carboxylated nitrogen-doped graphene, exhibit potent antibacterial properties against both Gram-negative and Gram-positive bacteria. Targeting the biomolecules of the outer bacterial membrane, the new “single-atom” engineered antibiotic effectively bypasses the development of bacterial resistance and heals infected wounds in vivo, while remaining non-toxic to human cells. More details can be found in article number 2410652 by Aristides Bakandritsos, Radek Zbořil, and co-workers.

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单原子工程抗生素克服细菌耐药性（Adv. Mater. 50/2024）

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来源期刊

Advanced Materials 工程技术-材料科学：综合

CiteScore

43.00

自引率

4.10%

发文量

2182

审稿时长

2 months

期刊介绍： Advanced Materials, one of the world's most prestigious journals and the foundation of the Advanced portfolio, is the home of choice for best-in-class materials science for more than 30 years. Following this fast-growing and interdisciplinary field, we are considering and publishing the most important discoveries on any and all materials from materials scientists, chemists, physicists, engineers as well as health and life scientists and bringing you the latest results and trends in modern materials-related research every week.