Formation of double emulsion droplets in flow-focusing microchips: a numerical parametric study

IF 2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Journal of Flow Chemistry Pub Date : 2024-09-27 DOI:10.1007/s41981-024-00337-w
Chengyi Hu, Fan Jiang, Ju Yan
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Abstract

A microfluidic chip is introduced for generating double emulsion droplets, consisting of a coaxial focusing center structure combined with a flow-focusing structure. The volume of fluid method (VOF) was adopted to numerically simulate and validate the formation of double emulsion droplets in the device. The impact of microfluidics on the dimensions and molding position of double emulsion droplets was examined under varying flow parameters and physical properties. Results demonstrate that the impact of the alteration in the flow rate of the middle phase is pivotal in the droplet generation process in comparison to the outer phase. An increase in the flow rate of the middle phase results in a notable enlargement of the double emulsion droplets. An increase in viscosity affects the forming regime, causing a transition in the droplet regime. Furthermore, interfacial tension exerts a notable impact on the positioning of droplet formation. The microfluidic device outlined in this paper effectively generates double emulsion droplets characterized by high monodispersity and excellent stability, which serves as a new reference for the practical generation of double emulsion droplets.

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流动聚焦微芯片中双乳液滴形成的数值参数研究
介绍了一种用于产生双乳液滴的微流控芯片,该芯片由同轴聚焦中心结构和流动聚焦结构相结合组成。采用流体体积法(VOF)对装置内双乳液滴的形成进行了数值模拟和验证。研究了不同流动参数和物性条件下微流体对双乳液滴尺寸和成型位置的影响。结果表明,与外相相比,中间相流速的变化对液滴形成的影响至关重要。中相流速的增加导致双乳液滴的显著增大。粘度的增加会影响形成状态,导致液滴状态的转变。此外,界面张力对液滴形成的位置有显著影响。本文所述的微流控装置可有效生成单分散性高、稳定性好的双乳液滴,为双乳液滴的实际生成提供了新的参考。
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来源期刊
Journal of Flow Chemistry
Journal of Flow Chemistry CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
6.40
自引率
3.70%
发文量
29
审稿时长
>12 weeks
期刊介绍: The main focus of the journal is flow chemistry in inorganic, organic, analytical and process chemistry in the academic research as well as in applied research and development in the pharmaceutical, agrochemical, fine-chemical, petro- chemical, fragrance industry.
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