The use of precision radiotherapy for the management of cancer related pain in the abdomen.

IF 1.9 4区医学 Q3 HEALTH CARE SCIENCES & SERVICES Current Opinion in Supportive and Palliative Care Pub Date : 2024-12-12 DOI:10.1097/SPC.0000000000000738

Aisling M Glynn, Yaacov R Lawrence, Laura A Dawson, Aisling S Barry

{"title":"The use of precision radiotherapy for the management of cancer related pain in the abdomen.","authors":"Aisling M Glynn, Yaacov R Lawrence, Laura A Dawson, Aisling S Barry","doi":"10.1097/SPC.0000000000000738","DOIUrl":null,"url":null,"abstract":"Purpose of review: Abdominal pain due to cancer is a significant and debilitating symptom for cancer patients, which is commonly undertreated. Radiotherapy (RT) for the management of abdominal cancer pain is underused, with limited awareness of its benefit. This review presents a discussion on current precision RT options for the management of cancer pain in the abdomen.Recent findings: Precision RT focuses on delivering targeted and effective radiation doses while minimizing damage to surrounding healthy tissues. In patients with primary or secondary liver cancer, RT has been shown to significantly improve liver related cancer pain in the majority of patients. Also, symptom sequelae of tumour thrombus may be relieved with the use of palliative RT. Similarly, single dose, high precision stereotactic RT to the celiac plexus has been shown to significantly improve pain in patients with pancreatic cancer. Pain response for adrenal metastases has been less commonly investigated, but small series suggest that stereotactic body RT may reduce or alleviate pain.Summary: RT is an effective option for the treatment of abdominal cancer pain. RT should be considered within the multidisciplinary treatment armamentarium, and may be successfully integrated, alone or in conjunction with other treatment modalities, in abdominal cancer related pain.","PeriodicalId":48837,"journal":{"name":"Current Opinion in Supportive and Palliative Care","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Supportive and Palliative Care","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/SPC.0000000000000738","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose of review: Abdominal pain due to cancer is a significant and debilitating symptom for cancer patients, which is commonly undertreated. Radiotherapy (RT) for the management of abdominal cancer pain is underused, with limited awareness of its benefit. This review presents a discussion on current precision RT options for the management of cancer pain in the abdomen.

Recent findings: Precision RT focuses on delivering targeted and effective radiation doses while minimizing damage to surrounding healthy tissues. In patients with primary or secondary liver cancer, RT has been shown to significantly improve liver related cancer pain in the majority of patients. Also, symptom sequelae of tumour thrombus may be relieved with the use of palliative RT. Similarly, single dose, high precision stereotactic RT to the celiac plexus has been shown to significantly improve pain in patients with pancreatic cancer. Pain response for adrenal metastases has been less commonly investigated, but small series suggest that stereotactic body RT may reduce or alleviate pain.

Summary: RT is an effective option for the treatment of abdominal cancer pain. RT should be considered within the multidisciplinary treatment armamentarium, and may be successfully integrated, alone or in conjunction with other treatment modalities, in abdominal cancer related pain.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

审查目的：癌症引起的腹痛是癌症患者的一个重要且令人衰弱的症状，但通常治疗不足。放射治疗（RT）在治疗腹部癌痛方面的应用不足，人们对其益处的认识有限。本综述讨论了目前治疗腹部癌痛的精确 RT 选项：精确放射治疗的重点在于提供有针对性的有效放射剂量，同时尽量减少对周围健康组织的损伤。在原发性或继发性肝癌患者中，大多数患者的肝脏相关癌痛都能通过 RT 得到明显改善。此外，姑息性 RT 还可缓解肿瘤血栓的后遗症症状。同样，对腹腔神经丛进行单剂量、高精度的立体定向 RT 也能明显改善胰腺癌患者的疼痛。对肾上腺转移瘤的疼痛反应研究较少，但小型系列研究表明，体部立体定向 RT 可以减轻或缓解疼痛：总结：RT 是治疗腹部癌痛的有效方法。应在多学科治疗方案中考虑 RT，RT 可单独或与其他治疗方式成功结合，用于腹部癌症相关疼痛的治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Current Opinion in Supportive and Palliative Care HEALTH CARE SCIENCES & SERVICES-

CiteScore

3.70

自引率

0.00%

发文量

期刊介绍： A reader-friendly resource, Current Opinion in Supportive and Palliative Care provides an up-to-date account of the most important advances in the field of supportive and palliative care. Each issue contains either two or three sections delivering a diverse and comprehensive coverage of all the key issues, including end-of-life management, gastrointestinal systems and respiratory problems. Current Opinion in Supportive and Palliative Care is an indispensable journal for the busy clinician, researcher or student.

期刊最新文献

Palliative radiation therapy for locally advanced breast cancer. The use of precision radiotherapy for the management of cancer related pain in the abdomen. Advances in breathlessness support services for people with serious illness. Bridging the care gap: radiation therapy in elderly and frail cancer patients. The gut microbiome and the brain.