Visually relevant on-bench through-focus analysis of intraocular lenses.

IF 2.9 2区 医学 Q2 BIOCHEMICAL RESEARCH METHODS Biomedical optics express Pub Date : 2024-11-27 eCollection Date: 2024-12-01 DOI:10.1364/BOE.540034
Harilaos S Ginis, Spyridon Tsoukalas, Dimitrios Christaras, Pablo Artal
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Abstract

Cataract surgery involves the implantation of an intraocular lens (IOL) to replace the opacified crystalline lens. Monofocal IOLs, the most common type, are intended to have the eye in focus at a given distance, usually at infinity. Simultaneous vision IOLs (SVIOLs) and extended depth of focus (EDOF) aim to minimize postoperative dependence on spectacles by providing either multiple foci or an extended depth of focus. These lenses utilize a variety of diffractive and refractive designs to achieve varied focal depths. While common optical testing methods based on the IOL's modulation transfer function (MTF) or resolving power at best focus are essential for quality control, they do not fully address the lenses' performance requirements in daily visual tasks such as reading in a variety of distances. The purpose of this work was to introduce a visually relevant on-bench test method, which includes an image analysis technique and a visual acuity-related image quality metric, to evaluate the through-focus performance of different commercially available IOLs. This method consists of recording a series of optotype images in a realistic eye model with the IOL, adjusting the stimulus vergence through a focus-tunable lens. We compare the results obtained with mono-focal, enhanced mono-focal, EDOF, and (diffractive) trifocal IOLs.

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对眼内透镜进行与视觉相关的台上透焦分析。
白内障手术包括植入眼内人工晶体(IOL),以取代混浊的晶状体。单焦点人工晶体是最常见的类型,其目的是让眼睛在特定距离(通常是无限远)对焦。同步视觉人工晶体(SVIOLs)和延伸焦深人工晶体(EDOF)旨在通过提供多个焦点或延伸焦深,尽量减少术后对眼镜的依赖。这些镜片利用各种衍射和折射设计来实现不同的焦深。虽然基于人工晶体的调制传递函数(MTF)或最佳聚焦时的分辨力的普通光学测试方法对于质量控制至关重要,但它们并不能完全满足镜片在日常视觉任务(如各种距离的阅读)中的性能要求。这项工作的目的是引入一种与视觉相关的台上测试方法,其中包括一种图像分析技术和一种与视觉敏锐度相关的图像质量指标,用于评估不同市售人工晶体的通焦性能。该方法包括在装有人工晶体的真实眼球模型中记录一系列光学图像,并通过焦点可调透镜调整刺激辐辏。我们比较了单焦点、增强型单焦点、EDOF 和(衍射)三焦点人工晶体获得的结果。
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来源期刊
Biomedical optics express
Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS
CiteScore
6.80
自引率
11.80%
发文量
633
审稿时长
1 months
期刊介绍: The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.
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